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Table 2 sFLC ratio distribution according to eGFR in the group of patients without active MM. sFLC ratio range increases when there is a decrease in eGFR. The number of false positives according to the the current normal range (Katzmann) also increases specially in patients with eGFR ≤55 ml/min

From: The renal range of the κ/λ sFLC ratio: best strategy to evaluate multiple myeloma in patients with chronic kidney disease

 

eGFR ≥ 90 (n = 76)

eGFR 56–89 (n = 70)

eGFR ≤ 55 (n = 30)

sFLC ratio (IQR)

1,04 (0,85-1,3)

1,11 (0,89-1,39)

1,31 (0,95-2,08)

False positives (%)

6/76 (7,9)

6/70 (8,5)

11/30 (36,7)

  1. eGFR Estimated Glomerular Filtration Rate, IQR Interquartile range, MM Multiple Myeloma, sFLC Serum Free Light-Chain
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BMC Nephrology

ISSN: 1471-2369

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