Benefits of peritoneal ultrafiltration in HFpEF and HFrEF patients

Grossekettler, Leonie; Schmack, Bastian; Brockmann, Carsten; Wanninger, Reinhard; Kreusser, Michael M.; Frankenstein, Lutz; Kihm, Lars P.; Zeier, Martin; Katus, Hugo A.; Schwenger, Vedat; Remppis, Andrew

doi:10.1186/s12882-020-01777-x

BMC Nephrology

Table 3 Clinical variables at baseline and after beginning of pUF^a. Median, standard deviation and students t-test for paired variables. Mean and Wilcoxon signed-rank text for not normally contributed paired variables

From: Benefits of peritoneal ultrafiltration in HFpEF and HFrEF patients

	Pre-pUF^a	Post-pUF^a
		3 months	P	6 months	P	12 months	P	Last follow up	P
NYHA^d
HFrEF^b	3.45 ± 0.52	2.80 ± 0.50	< 0.001	2.79 ± 0.71	0.001	2.53 ± 0.75	< 0.001	2.71 ± 0.72	< 0.001
HFpEF^c	3.19 ± 0.61	2.82 ± 0.56	0.002	2.44 ± 0.68	0.028	2.63 ± 0.69	0.045	2.72 ± 0.58	< 0.001
Systolic BP^e (mmHg)
HFrEF^b	108.4 ± 18.7	111.2 ± 18.9	0.674	111.6 ± 18.9	0.846	117.0 ± 23.1	0.875	108.2 ± 23.2	0.284
HFpEF^c	115.9 ± 20.7	120.1 ± 17.1	0.703	114.9 ± 20.6	0.680	110.1 ± 19.6	0.354	114.3 ± 22.8	0.799
Diastolic BP^e (mmHg)
HFrEF^b	68.4 ± 12.6	65.8 ± 11.7	0.001	67.2 ± 13.3	0.097	69.8 ± 17.0	0.270	66.3 ± 14.2	0.010
HFpEF^c	67.1 ± 10.1	64.7 ± 7.18	0.542	66.5 ± 10.0	0.639	64.2 ± 12.3	0.752	64.0 ± 11.1	0.533
EF^f (%)
HFrEF^b	25.9 ± 6.82	29.0 ± 8.30	0.081	29.6 ± 8.75	0.154	31.1 ± 12.8	0.281	30.4 ± 12.2	0.046
HFpEF^c	51.3 ± 7.77	48.2 ± 5.04	0.304	49.0 ± 4.56	0.404	47.0 ± 5.20	0.547	51.5 ± 8.86	0.189
Urine (ml)
HFrEF^b	1172.3 ± 759.7	1408.4 ± 697.9	0.199	1319.1 ± 701.3	0.298	1263.4 ± 606.5	0.079	1051.0 ± 676.3	0.637
HFpEF^c	1431.4 ± 1195.8	1118.3 ± 991.4	0.273	1225.0 ± 1198.9	0.522	1092.3 ± 818.5	0.764	984.6 ± 740.3	0.744
pUF^a (ml)
HFrEF^b	na^g	1180.6 ± 1391.5	na^g	1269.6 ± 1566.5	0.805	1020.3 ± 952.1	0.626	1306.8 ± 1284.7	0.870
HFpEF^c	na^g	979.7 ± 473.6	na^g	982.6 ± 442.4	0.335	1140.6 ± 552.6	0.757	997.8 ± 546.6	0.359
Body Weight (kg)
HFrEF^b	81.1 ± 14.6	76.7 ± 15.2	< 0.001	77.4 ± 14.5	0.002	76.7 ± 14.3	0.068	77.2 ± 15.6	0.003
HFpEF^c	86.9 ± 15.8	82.3 ± 13.3	< 0.005	80.8 ± 11.0	0.023	83.2 ± 16.4	0.046	83.1 ± 15.9	0.005

Data are presented as mean ± SD
^apUF (peritoneal ultrafiltration)
^bHFrEF (heart failure with reduced ejection fraction)
^cHFpEF (heart failure with preserved ejection fraction)
^dNYHA (New York Heart Association functional class)
^eBP (blood pressure)
^fEF (ejection fraction)
^gna (not applicable)

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ISSN: 1471-2369

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