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Table 4 Area under the curve to predict the diagnostic accuracy of parameters studied for severe grades of chronic histological changes (glomerular sclerosis, tubular atrophy and interstitial fibrosis) based on total score > 7

From: Sonographically determined kidney measurements are better able to predict histological changes and a low CKD-EPI eGFR when weighted towards cortical echogenicity

Variable

AUROC

p

Cut-off

Sensitivity

Specificity

SCr

0.703

0.035

7.5

90.0%

20.0%

CKD-EPI

0.728

0.018

11.5

94.0%

40.0%

CT

0.599

0.331

–

–

–

KL

0.607

0.266

–

–

–

KL/H

0.701

0.037

0.58

93.0%

30.0%

w-CT

0.799

0.003

4.92

92.9%

44.4%

w-KL

0.833

0.001

65.9

94.9%

20.0%

w-KL/H

0.845

< 0.001

0.43

94.8%

40.0%

  1. SCr serum creatinine, CKD-EPI chronic kidney disease epidemiology collaboration, CT cortical thickness, KL kidney length, KL/H kidney length/height ratio, w weighted for cortical echogenicity factor
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BMC Nephrology

ISSN: 1471-2369

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