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Table 1 Clinical and biochemical characteristics of all patients included

From: Timing of kidney biopsy in type 2 diabetic patients: a stepwise approach

Characteristics

Isolated DN

n = 120

NDRD ± DN

n = 40

P-value

Gender (male)

67 (55.8%)

32 (80%)

0.006

Age (year)

54.8 ± 11.7

64.8 ± 10.6

< 0.001

Body weight (kg)

67.3 (58.7, 75.4)

71.8 (63, 75.6)

0.246

Height (cm)

163 ± 8.5

162.9 ± 8 .2

0.919

BMI (kg/m2)

25.1 (22.5, 28.9)

26.1 (23.8, 28.5)

0.259

Duration of diabetes (yr)

10 (4, 16)

4 (1, 7.5)

< 0.001

Diabetic retinopathy

100 (83.3%)

12 (30%)

< 0.001

 PDR

56 (46.7%)

2 (5%)

< 0.001

 ME

15 (12.5%)

2 (5%)

0.244

 PRP

54 (45%)

2 (5%)

< 0.001

 PC

13 (10.8%)

0

0.039

 IVI

29 (24.2%)

1 (2.5%)

0.002

 VT

8 (6.7%)

0

0.202

HbA1c (%)

7.1 (6.1, 8.8)

6.7 (6, 7.5)

0.139

Serum creatinine (mg/dL)

2.8 (1.7, 4.7)

2.3 (1.5, 4.1)

0.256

eGFR (mL/min/1.73 m2)

21.1 (11.8, 40)

28.5 (13.4, 46)

0.257

UPCR (1000 mg/g)

9.1 (5.7, 12.3)

7.6 (3.2, 14.8)

0.546

Urinary red blood cells/HPF

4 (1.4, 8)

8 (4, 15.5)

< 0.001

Urinary white blood cells/HPF

1 (1, 4)

1 (1, 4)

0.307

Right kidney size (cm)

11.5 ± 1.1

11.1 ± 1.3

0.056

Left kidney size (cm)

11.5 ± 1.2

11.2 ± 1.2

0.214

  1. Values were presented as median (Q1, Q3), mean ± SD, or n (%)
  2. DN diabetic nephropathy, NDRD non-diabetic renal disease, BMI body mass index, PDR proliferative diabetic retinopathy, ME macular edema, PRP pan-retinal photocoagulation, PC focal photocoagulation, IVI intravitreal injection, VT vitrectomy, UPCR urine protein-to-creatinine ratio