Roles of peritoneal clearance and residual kidney removal in control of uric acid in patients on peritoneal dialysis

Table 5 Independent determinants of higher peritoneal UA clearance (> 39.8 L/week/1.73m²) in binary logistic regression in total, lower and higher mGFR patients, respectively

	Total		Lower mGFR group^a		Higher mGFR group
Variables	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
mGFR (mL/min/1.73m²)	0.96 (0.78, 1.18)	0.68	–	–	–	–
Age (y)	1.03 (1.00, 1.06)	0.07	1.01 (0.97, 1.05)	0.69	1.06 (1.01, 1.11)	0.03
Sex (M/F)	0.28 (0.12, 0.64)	0.003	0.28 (0.08, 1.00)	0.05	0.28 (0.09,0.90)	0.33
Using diuretics	0.63 (0.22, 1.85)	0.40	0.55 (0.11, 2.89)	0.48	0.81 (0.17,3.77)	0.78
Albumin (g/dL)	0.16 (0.05, 0.49)	0.001	0.08 (0.01, 0.47)	0.006	0.31 (0.06,1.54)	0.15
PD vintage (month)	1.00 (0.98, 1.02)	0.90	1.00 (0.98, 1.02)	0.97	0.99 (0.90,1.09)	0.82
BMI (kg/m²)	0.77 (0.67, 0.89)	0.001	0.79 (0.63, 0.99)	0.04	0.71 (0.57,0.89)	0.003
Average glucose concentration of dialysate (0.1%)	1.40 (1.07, 1.83)	0.02	1.56 (1.11, 2.19)	0.01	1.02 (0.58, 1.77)	0.96
Higher peritoneal transport status^b	4.48 (1.73,11.56)	0.002	3.90 (0.97, 15.67)	0.06	5.65 (1.25,25.54)	0.02
Dialysis dose (L/d)	2.25 (1.23, 4.13)	0.009	2.16 (0.88, 5.35)	0.10	2.12 (0.76,5.91)	0.15

Abbreviations: BMI body mass index, CI confidence interval, mGFR measured glomerular filtration rate, OR odds ratio, PD peritoneal dialysis, UA uric acid
^aDid not adjust mGFR when analyzing in the higher(> 2.74 mL/min/1.73m²) or lower (≤ 2.74 mL/min/1.73m²) mGFR group, respectively
^bThe reference group was the lower (low average or low) peritoneal transporters

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