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Table 1 Study characteristics

From: Systematic review and meta-analysis of clinical outcomes comparison between different initial dialysis modalities in end-stage renal disease patients due to lupus nephritis prior to renal transplantation

Study

Participants Number

Dialysis modality

HD, PD

Median Age HD, PD

Ethnicity/Race

Follow-up time HD; PD

Primary study aim

Country of study

Outcome measure

Kang 2011 [13]

59

28, 14

35, 41

Not Reported

5 ± 3; 5 ± 3 (Years)

Long-term outcome of patients with ESRD secondary to SLE who are managed by different types of RRTs

South Korea

LFR, IR, MR, PS

Tsai 2019 [19]

94

42, 12

36.40, 33.20

Not Reported

6.30 ± 5.10; 6.00 ± 5.20 (Years)

Long-term outcomes and survival rates of patients with ESRD caused by lupus nephritis who received 3 different modalities of renal replacement therapy

Taiwan

LFR, IR, MR, CVR, PS

Krane 1999 [20]

19

7, 5

32, 36

10 black, 2 Whites

3 years; 3 years

Lupus activity among patients with ESRD due to SLE, who were either undergoing dialysis or had undergone transplantation

USA

LFR

Chang 2013 [21]

1073

813, 260

42.60, 34.10

Not reported

≥ 3 months on RRT; ≥ 3 months on RRT

Mortality and the impact of dialysis modalities on the survival in SLE patients with end-stage renal disease (ESRD).

Taiwan

IR, MR, CVR, PS

Weng 2009 [22]

36

14, 22

48.70, 37.59

Not reported

126.83; 37 (Months)

Comparing PD and HD outcomes between female SLE patients with ESRD due to lupus nephropathy

Taiwan

IR, CVR, MR, PS

Wu 2014 [23]

1998

1640, 196

39.30, 36.20

Not Reported

3.31 ± 3.87; 4.34 ± 3.05 (Years)

Outcomes of patients with LN after progression to ESRD and to try to elucidate whether deferral of KT is necessary in the Chinese population.

Taiwan

MR, PS

Contreras 2014 [24]

11,023

1352, 1352

39,39

Caucasian American; African American; Asian Americans; Other Americans.

3 years; 3 years (Median)

Comparing the mortality risk of ESRD patients with SLE initiating with PD versus HD

USA

MR

Stock 1993 [31]

6

6, 6

Not Accessed

Not Accessed

Not Accessed

Determining if there was a difference in disease activity between treatment modalities, using patients as self-controls

USA

LFR

Zhu 2009 [32]

29

10, 19

34.50, 41.79

Not Reported

2 years; 2 years

Comparing 2-year outcome of ESRD in lupus nephritis patients in different dialysis modality.

China

LFR, IR, MR, CVR, PS

Ntatsaki 2018 [16]

361

17, 9

Not Accessed

Caucasian; Afro–Caribbean; South Asian

43 (Confidence interval13–49) (Months)

Investigating the time spent on dialysis before RT and survival ollowing RT in a cohort of SLE patients.

UK

MR

Zhang 2016 [33]

425

314, 111

Not Accessed

European; Maori and Pacific Islanders; Asian; Others

3.80 Years (Median); 3.80 Years (Median)

Comparing dialysis and transplant outcomes for patients with ESRD due to lupus nephritis to all other causes

Australia

MR

Levy 2015 [34]

368

308, 60

43.50, 43.90

Not Reported

5 Years; 5 Years

Describing the outcomes of SLE on chronic dialysis

France

MR, CVR

Mustapic 2013 [35]

7

6, 1

Not Accessed

Not Reported

Up to 10 years

Evaluating outcomes of pediatric patients with ESRD due to lupus nephritis and to determine has intensive specific treatment in SLE decreased incidence of ESRD and need for RRT, dialysis and kidney transplantation, in pediatric patients in the last 4 decades in Croatia

Croatia

MR

Kang 2010 [36]

59

28, 14

Not Accessed

 

5 ± 3 Years; 5 ± 3 Years;

Demonstrating the long-term outcome of lupus patients that underwent different RRTs including kidney transplantation

South Korea

LFR, CVR

Oliveira 2012 [37]

50

11, 2

Not Accessed

Non-Caucasians

11 Months;30 Months

Determining the epidemiological profile and outcome of patients with LN undergoing renal transplantation.

Brazil

LFR, MR

Lee 2003 [38]

26

20, 6

Not Accessed

Not recorded

57.50 ± 4.20 Months

Investigating the long-term prognosis of 26 SLE patients who started regular dialysis at a Chinese hospital whose stay exceeded a 3-month duration.

Taiwan

MR

  1. Abbreviations: IR infection risk, LFR lupus flare risk, CVR cardiovascular events risk, MR mortality risk, PS patients survival, LN lupus nephritis, RRT renal replacement therapy, SLE systemic lupus erythematosus, RT renal transplant, PD peritoneal dialysis, HD hemodialysis