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Table 2 Univariate Cox regression for stroke and composite endpoints

From: Effects of parathyroid hormone and vitamin D supplementation on stroke among patients receiving peritoneal dialysis

Variables

Model 1

Model 2

HR [95% CI]

p-value

HR [95% CI]

p-value

Age (years)

1.07 [1.05, 1.09]

< 0.001

1.05 [1.04, 1.06]

< 0.001

Gender (male)

0.72 [0.44, 1.18]

0.2

1.58 [1.13, 2.22]

0.008

Serum albumin (g/l)

0.96 [0.92, 1.00]

0.07

0.96 [0.94, 0.99]

0.005

Serum UA (mg/dl)

0.97 [0.86, 1.10]

0.6

0.98 [0.91, 1.07]

0.7

Hemoglobin (g/l)

1.00 [0.99, 1.01]

0.9

1.00 [0.99, 1.01]

0.5

Serum calcium (mmol/l)

1.44 [0.57, 3.63]

0.4

1.03 [0.57, 1.86]

0.9

Serum phosphorus (mmol/l)

0.55 [0.30, 1.03]

0.06

0.60 [0.40, 0.90]

0.01

iPTH levels

  ≤ 150

Ref

–

Ref

–

 150–300

0.43 [0.23, 0.81]

0.009

0.81 [0.54, 1.22]

0.3

 300–600

0.38 [0.20, 0.72]

0.003

0.54 [0.35, 0.84]

0.006

  > 600

0.58 [0.25, 1.33]

0.2

0.62 [0.34, 1.13]

0.1

SBP (mmHg)

1.00 [0.99, 1.01]

0.5

1.00 [0.99, 1.01]

0.9

DBP (mmHg)

0.97 [0.95, 0.98]

< 0.001

0.98 [0.97, 0.99]

< 0.001

Chronic heart disease (yes)

3.19 [1.95, 5.22]

< 0.001

3.04 [2.19, 4.23]

< 0.001

Atrial fibrillation (yes)

2.52 [1.09, 5.85]

0.03

2.88 [1.68, 4.92]

< 0.001

Diabetes (yes)

2.81 [1.72, 4.59]

< 0.001

2.43 [1.75, 3.37]

< 0.001

Vitamin D (yes)

0.38 [0.23, 0.63]

< 0.001

0.46 [0.32, 0.64]

< 0.001

Antiplatelet agents (yes)

3.33 [1.99, 5.58]

< 0.001

1.67 [1.20, 2.32]

0.002

Anticoagulants (yes)

0.72 [0.10, 5.22]

 

0.7

2.39 [1.12, 5.11]

0.02

Calcium agents (yes)

0.53 [0.31, 0.92]

 

0.02

0.68 [0.46, 1.00]

0.05

Statins (yes)

1.38 [0.80, 2.37]

0.3

0.82 [0.58, 1.14]

0.2

  1. Model 1: Univariate model for stroke; Model 2: Univariate model for composite endpoints