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Table 4 Predictive factors for uPCR < 1 mg/mg at 5 years posttreatment

From: Urinary angiotensinogen as a surrogate marker predicting the antiproteinuric effects of angiotensin receptor blockers in patients with overt proteinuria: a multicenter prospective study

 

Model 1a

Model 2b

Model 3c

OR

95% CI

P

OR

95% CI

P

OR

95% CI

P

ln(uAGT/Cr) (μg/g)

0.971

0.654–1.441

0.882

1.548

0.868–2.760

0.139

0.898

0.586–1.374

0.620

Δln(uAGT/Cr) (μg/g) d

0.361

0.195–0.668

0.001

0.287

0.126–0.654

0.003

0.379

0.201–0.715

0.003

ln(uR/Cr) (pg/g)

0.945

0.652–1.363

0.753

1.105

0.733–1.666

0.633

1.020

0.691–1.505

0.922

  1. Abbreviations: CI confidence interval, OR odds ratio, uAGT/Cr urinary angiotensinogen/creatinine ratio, uR/Cr urinary renin/creatinine ratio
  2. aModel 1: Adjusted for diabetes mellitus, hypertension, and baseline eGFR
  3. bModel 2: Adjusted for baseline uPCR, diabetes mellitus, hypertension, and baseline eGFR
  4. cModel 3: Adjusted for ΔuPCR at 24 weeks (uPCR at 24 weeks - baseline uPCR), diabetes mellitus, hypertension, and baseline eGFR
  5. dΔln(uAGT/Cr) = [ln(uAGT/Cr) at 24 weeks] - [baseline ln(uAGT/Cr)]