Table 2 Association Between Baseline Serum Chloride and > 30% Decline in eGFR
From: The association between serum chloride levels and chronic kidney disease progression: a cohort study
Cox Model | Hazard-Ratio Estimate | 95% C.I. | P-value |
|---|---|---|---|
Continuous serum chloride (per 1 mEq/L increase) | |||
Unadjusted | 1.097 | (1.045, 1.152) | < 0.001 |
Demographic adjusted | 1.082 | (1.029, 1.138) | 0.002 |
Fully adjusted | 1.051 | (0.99, 1.116) | 0.10 |
Chloride quartiles (unadjusted) | |||
1 | Ref | Ref | |
2 | 1.205 | (0.662, 2.195) | 0.54 |
3 | 1.105 | (0.596, 2.052) | 0.75 |
4 | 1.97 | (1.135, 3.417) | 0.02 |
Measured ordinally | 1.259 | (1.053, 1.504) | 0.01 |
Chloride quartiles (demographic adjusted) | |||
1 | Ref | Ref | |
2 | 1.188 | (0.645, 2.188) | 0.58 |
3 | 1.129 | (0.605, 2.106) | 0.70 |
4 | 1.683 | (0.957, 2.961) | 0.007 |
Measured ordinally | 1.182 | (0.976, 1.011) | 0.07 |
Chloride quartiles (fully adjusted) | |||
1 | Ref | Ref | |
2 | 1.104 | (0.588, 2.07) | 0.76 |
3 | 1.11 | (0.581, 2.124) | 0.75 |
4 | 1.271 | (0.676, 2.393) | 0.46 |
Measured ordinally | 1.080 | (0.877, 1.330) | 0.47 |