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Fig. 4 | BMC Nephrology

Fig. 4

From: Ion-Channel modulator TH1177 reduces glomerular injury and serum creatinine in chronic mesangial proliferative disease in rats

Fig. 4

a shows representative examples of PMT stained renal sections from the animals with chronic thy1 nephritis for the 3 treatment groups (vehicle treated, late TH1177 treated and early TH1177 treated). The blue stain indicates matrix deposition seen maximally in the vehicle treated animals. Scale bars are 100 μm. b shows the area of aniline blue staining by automated image analysis in the 3 treatment groups. c shows the categories of glomerular damage quantified in the 3 groups. Significant differences from vehicle-treated are indicated * for p < 0.05 and ** for p < 0.01. Error bars are S.E.M.

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