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Table 2 Risk factors for AKI development using logistic regression analysis. a (N = 850)

From: Incidence of acute kidney injury and use of renal replacement therapy in intensive care unit patients in Indonesia

Characteristicsb

Unadjusted OR

(95% CI)

P-value

Adjusted OR

(95% CI)

P-value

Age, 10-year increment

1.11 (1.02, 1.22)

0.019

0.90 (0.80, 1.02)

0.11

Male sex

0.93 (0.70, 1.22)

0.60

  

Reimbursement,N = 834

 - Government officer

0.98 (0.74, 1.29)

0.87

  

 - Social security system

Reference

   

 - Private health insurance /Cash/self-pay

1.18 (0.53, 2.61)

0.69

  

BMI

 - Underweight

1.60 (0.76, 3.36)

0.22

1.18 (0.48, 2.91)

0.73

 - Normal

Reference

 

Reference

 

 - Overweight / obese

1.67 (1.14, 2.47)

0.009

1.55 (0.97, 2.49)

0.07

Primary diagnosis,N = 846

 - Cardiovascular diseases

0.90 (0.64, 1.26)

0.53

  

 - Endocrine Diseases

2.31 (1.08, 4.95)

0.032

0.97 (0.38, 2.49)

0.95

 - Gastrointestinal Diseases

1.94 (0.94, 4.02)

0.07

1.20 (0.49, 2.99)

0.69

 - Hematologic Diseases

1.37 (0.09, 21.99)

0.82

  

 - Infectious Diseases

3.81 (2.02, 7.17)

< 0.001

1.15 (0.51, 2.57)

0.74

 - Neurologic Diseases

2.06 (1.35, 3.15)

0.001

0.97 (0.53, 1.77)

0.92

 - Oncologic Diseases

1.27 (0.57, 2.83)

0.55

  

 - Renal Diseases

3.87 (1.61, 9.31)

0.003

4.53 (1.67, 12.33)

0.003

 - Respiratory Diseases

2.92 (1.61, 5.32)

< 0.001

1.53 (0.72, 3.25)

0.27

 - Surgical related diseases

0.27 (0.20, 0.37)

< 0.001

0.60 (0.39, 0.93)

0.021

Comorbidity

 - HT

0.88 (0.66, 1.16)

0.35

  

 - DM

2.05 (1.52, 2.77)

< 0.001

1.08 (0.73, 1.61)

0.71

 - Cerebrovascular

3.83 (1.21, 12.13)

0.022

1.55 (0.39, 6.17)

0.53

 - Malignancy

1.02 (0.55, 1.91)

0.95

  

 - CAD

0.47 (0.27, 0.81)

0.006

0.50 (0.26, 0.98)

0.042

APACHE-II score

1.21 (1.17, 1.25)

per 1-point increase

< 0.001

1.14 (1.09, 1.20)

per 1-point increase

< 0.001

Non-renal SOFA score

1.62 (1.49, 1.76)

per 1-point increase

< 0.001

1.14 (1.00,1.31)

per 1-point increase

0.050

Vasopressors

13.08 (4.61, 37.17)

< 0.001

2.99 (0.93, 9.62)

0.067

Mechanical ventilation

4.76 (3.49, 6.51)

< 0.001

1.29 (0.80, 2.08)

0.30

  1. Chronic kidney disease (CKD) was not included in this analysis because there was small number of CKD patients in non-AKI group
  2. BMI Body mass index, DM Diabetes mellitus, CAD Coronary artery disease, CVD Cerebrovascular disease, APACHE II Acute physiologic and chronic health evaluation I, SOFA Sequential organ failure assessment
  3. a15 participants who had AKI as the primary diagnosis for ICU admission were excluded from the analysis
  4. bAll these parameters came from the first day of ICU admission