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Table 3 Patients’ characteristics and risk factors for severe AKI using logistic regression analysis (N = 373)

From: Incidence of acute kidney injury and use of renal replacement therapy in intensive care unit patients in Indonesia

Characteristicsa

Unadjusted OR

(95% CI)

P-value

Adjusted OR

(95% CI)

P-value

Age, 10-year increment

0.93 (0.81, 1.07)

0.284

  

Male sex

1.93 (1.27, 2.94)

0.002

2.47 (1.48, 4.12)

0.001

Reimbursement,N = 361

 - Government officer

1.04 (0.68, 1.59)

0.85

  

 - Social security system

Reference

   

 - Private health insurance/Cash/self-pay

0.35 (0.09, 1.36)

0.13

  

BMI

 - Underweight

2.32 (0.82, 6.56)

0.11

2.26 (0.7, 7.32)

0.18

 - Normal

Reference

 

Reference

 

 - Overweight / obese

3.74 (2.10, 6.65)

< 0.001

2.26 (0.7, 7.32)

0.18

Primary diagnosis,N = 370

 - Cardiovascular diseases

0.78 (0.46, 1.31)

0.35

  

 - Endocrine Diseases

0.51 (0.19, 1.39)

0.19

0.41 (0.12, 1.44)

0.16

 - Gastrointestinal Diseases

0.65 (0.25, 1.74)

0.40

  

 - Hematologic Diseases

NA

   

 - Infectious Diseases

2.00 (0.98, 4.07)

0.058

1.24 (0.51, 2.97)

0.64

 - Neurologic Diseases

1.31 (0.75, 2.28)

0.35

  

 - Oncologic Diseases

1.06 (0.33, 3.34)

0.92

  

 - Renal Diseases

3.00 (1.30, 6.97)

0.010

1.5 (0.5, 4.56)

0.47

 - Respiratory Diseases

1.36 (0.68, 2.71)

0.38

  

 - Rheumatologic Diseases

2.12 (0.19, 23.62)

0.54

  

 - Surgical related diseases

0.50 (0.30, 0.82)

0.006

0.8 (0.43, 1.49)

0.48

Comorbidity

 - HT

1.29 (0.85, 1.96)

0.23

  

 - DM

1.70 (1.11, 2.58)

0.014

1.15 (0.65, 2.02)

0.63

 - CKD

12.91 (4.51, 36.96)

< 0.001

9.47 (3.1, 28.91)

< 0.001

 - Cerebrovascular

0.39 (0.10, 1.48)

0.17

  

 - Malignancy

2.20 (0.81, 5.99)

0.12

3.43 (1.11, 10.57)

0.032

 - CAD

0.95 (0.38, 2.40)

0.92

  

APACHE-II scorea

1.07 (1.04, 1.10)

per 1-point increase

< 0.001

1.07 (1.01, 1.13)

per 1-point increase

0.018

Non-renal SOFA scorea

1.14 (1.05, 1.24)

per 1-point increase

0.002

0.92 (0.78, 1.08)

per 1-point increase

0.29

Vasopressors

9.29 (3.55, 24.26)

< 0.001

5.41 (1.8, 16.29)

0.003

Mechanical ventilation

1.70 (1.13, 2.55)

0.012

1.31 (0.69, 2.49)

0.41

  1. NA: not included in the multivariable model even though the P-value was < 0.20 because there were limited data
  2. BMI Body mass index, DM Diabetes mellitus, CAD Coronary artery disease, CVD Cerebrovascular disease, APACHE II Acute physiologic and chronic health evaluation II, SOFA Sequential organ failure assessment
  3. aAll of these parameters came from the first day of ICU admission
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BMC Nephrology

ISSN: 1471-2369

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