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Table 1 Mean ADC (× 10− 3 mm2/s), FA and R2* (1/s) values at different time points during CI-AKI (n = 6)

From: Application of diffusion tensor imaging and blood oxygenation level-dependent magnetic resonance imaging to assess bilateral renal function induced by Iohexol in rabbits

 

Baseline

1 h

24 h

48 h

72 h

ADC

 CO Right

1.66 ± 0.02

1.45 ± 0.03*

1.22 ± 0.03*

1.49 ± 0.03*

1.63 ± 0.02

  Left

1.66 ± 0.02

1.49 ± 0.02*

1.29 ± 0.02*

1.51 ± 0.03*

1.64 ± 0.02

 OM Right

1.59 ± 0.03

1.36 ± 0.02*

1.17 ± 0.03*

1.41 ± 0.02*

1.59 ± 0.03

  Left

1.59 ± 0.02

1.40 ± 0.02*

1.25 ± 0.03*

1.43 ± 0.02*

1.58 ± 0.03

 IM Right

1.57 ± 0.03

1.34 ± 0.02*

1.15 ± 0.03*

1.39 ± 0.02*

1.57 ± 0.03

  Left

1.57 ± 0.02

1.38 ± 0.02*

1.22 ± 0.03*

1.41 ± 0.02*

1.56 ± 0.03

FA

 CO Right

0.39 ± 0.01

0.31 ± 0.01*

0.27 ± 0.02*

0.34 ± 0.01*

0.39 ± 0.02

  Left

0.39 ± 0.01

0.34 ± 0.01*

0.31 ± 0.02*

0.35 ± 0.01*

0.38 ± 0.02

 OM Right

0.41 ± 0.01

0.35 ± 0.02*

0.27 ± 0.02*

0.37 ± 0.02*

0.39 ± 0.01

  Left

0.40 ± 0.01

0.37 ± 0.01*

0.31 ± 0.01*

0.38 ± 0.01*

0.39 ± 0.01

 IM Right

0.49 ± 0.02

0.41 ± 0.01*

0.35 ± 0.02*

0.44 ± 0.01*

0.49 ± 0.02

  Left

0.49 ± 0.02

0.44 ± 0.02*

0.39 ± 0.02*

0.45 ± 0.01*

0.49 ± 0.02

R2*

 CO Right

17.57 ± 1.09

23.78 ± 1.18*

25.68 ± 1.95*

22.41 ± 1.96*

18.98 ± 1.07

  Left

17.49 ± 1.26

22.44 ± 1.05*

23.87 ± 0.83*

21.24 ± 2.02*

18.81 ± 1.36

 OM Right

22.45 ± 0.95

28.25 ± 1.18*

34.16 ± 1.05*

28.67 ± 0.85*

23.64 ± 2.14

  Left

22.01 ± 0.81

25.54 ± 0.90*

28.60 ± 0.87*

26.25 ± 1.19*

23.09 ± 1.77

 IM Right

19.05 ± 1.25

25.68 ± 0.99*

29.71 ± 0.82*

22.65 ± 1.35*

19.84 ± 1.32

  Left

18.56 ± 1.12

22.91 ± 0.70*

25.56 ± 0.76*

20.99 ± 1.29*

19.24 ± 1.38

  1. Repeated measures ANOVA Bonferroni P-value and one-way ANOVA Tukey P-value. All data are presented as the mean ± standard deviation (SD)
  2. CI-AKI contrast-induced acute kidney injury, CO cortex, OM outer medulla, IM inner medulla
  3. *P < 0.05 (vs. baseline)