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Fig. 5 | BMC Nephrology

Fig. 5

From: Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in rats

Fig. 5

BBG reduces the immunoexpression of TGF-β in UUO. a Graphical representation of TGF-β surface density in renal cortex. The graphic presents aligned dot plot and mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. # p < 0.05 vs UUO-V and both SHAM groups. b Representative immunostaining of the renal cortex from UUO-V group and c UUO-BBG group. d Graphical representation of TGF-β surface density in renal medulla. The graphic shows aligned dot plot and mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. # p < 0.05 vs UUO-V and both SHAM groups. e Representative immunostaining of the renal medulla from UUO-V group and f UUO-BBG group. All pictures of the sham control groups are shown in the supplementary material. Bar = 100 μm for all figures

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