Table 3 Multiple regression analysis of serum creatinine levels at renal biopsy and histological variables
Variable | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
Coeff [95% CI] | Coeff [95% CI] | Coeff [95% CI] | |
Active lesions | |||
Endocapillary proliferation | 0.15 [− 0.22 to 0.51] | 0.16 [− 0.20 to 0.52] | 0.16 [− 0.2 to 0.52] |
Karyorrhexis | 0.08 [− 1.34 to 1.51] | 0.20 [− 0.74 to 1.15] | 0.23 [− 0.71 to 1.17] |
Fibrinoid necrosis | 0.18 [− 1.08 to 1.45] | ||
Rupture of glomerular basement membranes | 0.16 [− 3.54 to 3.85] | 0.34 [− 2.83 to 3.52] | 0.39 [− 2.79 to 3.56] |
Extracapillary proliferation | 0.37 [− 0.77 to 1.51] | 0.40 [− 0.73 to 1.52] | 0.42 [− 0.7 to 1.54] |
Wire loop lesions | 0.13 [− 0.22 to 0.48] | 0.12 [− 0.22 to 0.47] | 0.08 [− 0.26 to 0.42] |
Hyaline deposits | −1.84 [− 3.64 to − 0.04] | − 1.78 [− 3.56 to − 0.00] | − 1.67 [− 3.43 to 0.09] |
Membranous lesions | −0.17 [− 0.50 to 0.17] | −0.19 [− 0.51 to 0.13] | −0.15 [− 0.48 to 0.17] |
Monocellular infiltration (category) | 0.22 [− 0.36 to 0.80] | 0.26 [0.04 to 0.47] | |
Chronic lesions | |||
Glomerular sclerosis | 1.10 [0.43 to 1.76] | 1.08 [0.43 to 1.74] | 1.07 [0.43 to 1.72] |
Fibrous adhesion | 0.73 [−0.69 to 2.14] | 0.68 [−0.72 to 2.08] | 0.79 [− 0.61 to 2.19] |
Fibrous crescents | −1.30 [− 3.91 to 1.31] | −1.31 [− 3.84 to 1.21] | − 1.32 [− 3.84 to 1.21] |
Interstitial fibrosis (category) | 0.06 [− 0.52 to 0.65] | 0.27 [0.05 to 0.49] | |
Arteriosclerosis (category) | − 0.04 [− 0.29 to 0.21] | −0.02 [− 0.26 to 0.23] | − 0.02 [− 0.26 to 0.23] |