Association of overweight with postoperative acute kidney injury among patients receiving orthotopic liver transplantation: an observational cohort study

Table 3 Association of Overweight with Postoperative AKI

Outcome	Model 1		Model 2		Model 3
Outcome	OR (95%CI)	P Value	OR (95%CI)	P Value	OR (95%CI)	P Value
AKI
Normal weight	1 (reference)		1 (reference)		1 (reference)
Underweight	0.360 (0.083–1.570)	0.174	0.240 (0.051–1.140)	0.073	0.219 (0.045–1.063)	0.059
Overweight	1.745 (0.962–3.168)	0.067	1.820 (0.985–3.363)	0.056	1.781 (0.962–3.297)	0.066
Obese	2.200 (0.586–8.260)	0.243	2.522 (0.633–10.052)	0.190	2.427 (0.608–9.684)	0.209
Severe AKI (stage 2/3)
Normal weight	1 (reference)		1 (reference)		1 (reference)
Underweight	–	–	–	–	–	–
Overweight	2.266 (1.290–3.980)	0.004	2.560 (1.401–4.678)	0.002	2.539 (1.389–4.642)	0.002
Obese	2.487 (0.818–7.559)	0.108	3.741 (1.119–12.510)	0.032	3.705 (1.108–12.388)	0.033

Note: - not available
Model 1 was unadjusted
Model 2 was adjusted for a priori defined variables based on literature research and clinical relevance (female gender, CTP score, MELD score, pre-existing CKD, pre-existing DM, preoperative Scr, requirement of vasopressors, postoperative peak AST, Tacrolimus)
Model 3 was adjusted for the same variables as model 2 and for potential confounding factors based on univariate analyses (female gender, preoperative Scr, preoperative lactic acid, intraoperative RBC transfusion)

ISSN: 1471-2369