Table 1 Baseline demographic and clinical data in the patients with and without AKD

 Age (years)

64 ± 1

68 ± 1

61 ± 1

< 0.001

 Gender, Male(%)

202(75)

97(76)

105(74)

NS(0.888)

 Body weight (kg)

66.3 ± 0.8

65.2 ± 1.1

67.4 ± 1.0

NS(0.157)

 Diabetes mellitus, n(%)

110(41)

58(45)

52(37)

NS(0.173)

 Hypertension, n(%)

163(61)

85(66)

78(55)

NS(0.08)

 Sepsis, n(%)

15(5.6)

15(12)

0(0)

0.001

 Body temperature (°C)

36.9 ± 0.1

37.1 ± 0.1

36.8 ± 0.1

0.026

 Respiratory rate(/min)

22 ± 0

23 ± 1

21 ± 0

< 0.001

 Mean arterial pressure (mmHg)

90 ± 3

92 ± 7

89 ± 1

NS(0.608)

 Blood sugar (mg/dl)

160 ± 5

166 ± 9

155 ± 6

NS(0.288)

 Serum IL-18 (ng/ml)

350 ± 20

454 ± 36

256 ± 15

< 0.001

 Urine IL-18 (ng/ml)

61 ± 2

64 ± 3

59 ± 2

NS(0.165)

 Serum NGAL (ng/ml)

112 ± 9

138 ± 14

88 ± 10

0.004

 Urine NGAL (ng/ml)

46 ± 10

77 ± 20

20 ± 4

0.007

 Serum CysC (mg/L)

1.9 ± 0.1

2.4 ± 0.2

1.5 ± 0.1

0.001

 Urine CysC (mg/L)

1.0 ± 0.5

1.8 ± 1.1

0.4 ± 0.2

NS(0.213)

 Serum creatinine baseline (mg/dL)

1.36 ± 0.07

1.44 ± 0.09

1.15 ± 0.10

0.029

 Serum creatinine 0–24 h (mg/dL)

1.64 ± 0.13

1.96 ± 0.18

1.07 ± 0.14

< 0.001

 Serum creatinine 24–48 h (mg/dL)

1.50 ± 0.13

1.81 ± 0.18

0.93 ± 0.07

< 0.001

 Serum creatinine 48–72 h (mg/dL)

1.49 ± 0.11

1.79 ± 0.16

1.02 ± 0.12

< 0.001

 Serum creatinine 7-day (mg/dL)

1.87 ± 0.20

1.96 ± 0.21

0.89 ± 0.13

< 0.001

 Serum creatinine 1-month (mg/dL)

1.60 ± 0.13

1.68 ± 0.15

1.28 ± 0.25

NS(0.208)

 Serum creatinine 3-month (mg/dL)

1.59 ± 0.14

1.64 ± 0.16

1.31 ± 0.31

NS(0.397)

 Hemoglobin (g/dL)

12.9 ± 0.15

12.0 ± 0.2

13.7 ± 0.2

< 0.001

 Leukocytes (×10³/μL)

9.5 ± 0.3

10.0 ± 0.6

9.1 ± 0.3

NS(0.174)

 Serum sodium (mmol/L)

139 ± 0

139 ± 0

139 ± 0

NS(0.379)

 hsCRP (mg/L)

31 ± 3

42 ± 6

20 ± 3

0.001

 Troponin I (ng/ml)

6.6 ± 1.0

5.4 ± 1.2

7.7 ± 1.7

NS(0.272)

 BNP (pg/ml)

725 ± 70

1025 ± 106

382 ± 71

< 0.001

 Ejection fraction (%)

54 ± 1

51 ± 2

57 ± 1

0.004

 Albumin (g/L)

3.7 ± 0.0

3.5 ± 0.1

3.9 ± 0.0

< 0.001