Pathological characteristics | Non-DM (n = 164) | DM (n = 42) | P-value |
---|---|---|---|
Ehrenreich-Churg stage | Â | Â | 0.578 |
MN I + II (n, %) | 124 (75.6) | 30 (71.4) |  |
MN III + IV (n, %) | 40 (24.4) | 12 (28.6) |  |
Glomerular sclerosis (n, %) | |||
Global sclerosis | 39 (23.8) | 9 (21.4) | 0.748 |
Segmental sclerosis | 35 (21.3) | 8 (19.4) | 0.744 |
Tubular atrophy (n, %) | Â | Â | 0.889 |
Atrophy area < 25% | 157 (95.7) | 40 (95.2) |  |
Atrophy area ≥ 25% | 7 (4.3) | 2 (4.8) |  |
Interstitial ICI (n, %) | 143 (87.2) | 38 (90.5) | 0.561 |
Interstitial fibrosis (n, %) | 54 (32.9) | 14 (33.3) | 0.960 |
Renal arteriopathy (n, %) | 131 (79.9) | 33 (78.6) | 0.851 |
IgG subgroup deposit (n, %) | |||
IgG1 (n, %) | 133 (81.1) | 35 (83.3) | 0.739 |
IgG2 (n, %) | 103 (62.8) | 26 (61.9) | 0.914 |
IgG3 (n, %) | 73 (44.5) | 18 (42.9) | 0.847 |
IgG4 (n, %) | 155 (94.5) | 39 (92.9) | 0.683 |
IgA deposit (n, %) | 4 (2.4) | 2 (4.8) | 0.424 |
IgM deposit (n, %) | 137 (83.5) | 34 (81.0) | 0.691 |
C3 deposit (n, %) | 158 (96.3) | 42 (100) | 0.350 |
C1q deposit (n, %) | 5 (3.0) | 3 (7.1) | 0.220 |
Positive PLA2R deposit (n, %) | 127 (77.4) | 35 (83.3) | 0.406 |
Positive THSD7A deposit (n, %)a | 0 (0) | 0 (0) | – |
Average GBMT (nm) | 1440 ± 338 | 1524 ± 316 | 0.150 |