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Table 1 Clinical and biochemical characteristics of type 2 diabetes subjects categorized according to eGFR

From: Association of urinary non-albumin protein with the different urinary marker for glomerular and tubular damage in patients with type 2 diabetes

Variables Group 1
eGFR (≥60 mL/min/1.73 m2)
Group 2
eGFR (< 60 mL/min/1.73 m2)
p value
N 269 155  
Age, years 54.67 ± 6.04 56.08 ± 6.54 0.026
Male gender (%) 45.0 43.9 0.840
BMI, kg/m2 32.27 ± 5.53 32.49 ± 6.00 0.703
Duration of diabetes, years 17.84 ± 5.26 19.10 ± 6.16 0.026
SBP, mmHg 134.54 ± 18.26 141.50 ± 21.00 <0.001
DBP, mmHg 73.79 ± 10.50 73.89 ± 11.50 0.927
FBS, mg/dL 207.04 ± 87.01 234.44 ± 101.64 0.004
HbA1c, % 10.31 ± 1.59 10.76 ± 2.08 0.012
Total cholesterol, mg/dL 175.81 ± 39.05 198.83 ± 55.03 <0.001
LDL, mg/dL 132.06 ± 40.11 138.29 ± 51.43 0.169
HDL, mg/dL 45.31 ± 11.07 47.81 ± 13.60 0.041
Triglycerides, mg/dL 166.46 ± 80.12 203.57 ± 87.33 <0.001
ACR, mg/g median (IQR) 15.59(5.96–57.67) 167.50(50.66–634.85) <0.001
PCR, mg/g median (IQR) 118.70(68.32–238.59) 297.37(155.54–1122.93) < 0.001
NAPCR, mg/g median (IQR) 88.15(50.89–181.95) 186.13(75.09–613.93) <0.001
Transferrin/Cr, μg/g median (IQR) 348.87(140.82–1021.62) 1334.19(422.58–3117.02) <0.001
RBP/ Cr, μg/g median (IQR) 315.67(202.93–503.68) 572.96(305.82–1589.01) <0.001
NGAL/Cr, μg/g median (IQR) 23.47(11.64–48.42) 36.48(15.83–89.87) <0.001
  1. Group 1,eGFR ≥60 mL/min/1.73 m2; Group 2, eGFR <60 mL/min/1.73 m2; BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBS Fasting blood sugar, HbA1c Hemoglobin A1c, LDL Low-density lipoprotein, HDL High-density lipoprotein, ACR Albumin-to-creatinine ratio, PCR Total protein-to-creatinine ratio, NAPCR Non-albumin protein -to-creatinine ratio, Transferrin/Cr Transferrin-to-creatinine ratio, RBP/Cr Retinol binding protein-to-creatinine ratio, NGAL/Cr Neutrophil gelatinase-associated lipocalin-to-creatinine ratio, eGFR Estimated glomerular filtration rate. Data are presented as mean ± standard deviation for parametric variables and median (IQR; Inter quartile range) (25th and 75th) for non-parametric variables and compared by ANOVA. Categorical data are presented as absolute frequencies and compared using the Chi-square test. Values of p < 0.05 were considered significant