Skip to main content

Table 3 Multivariate regression analysis with non-albumin protein-to-creatinine ratio as the dependent variable

From: Association of urinary non-albumin protein with the different urinary marker for glomerular and tubular damage in patients with type 2 diabetes

  Total patients (424) Group 1 (269) Group 2 (155)
  Model 1 Model 2 Model 3 Model 1 Model 2 Model 3 Model 1 Model 2 Model 3
  adj R2 adj R2 adj R2 adj R2 adj R2 adj R2 adj R2 adj R2 adj R2
ACR 0.089 0.103 0.419 0.234 0.511 0.566 0.157 0.160 0.412
p value <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
PCR 0.055 0.066 0.379 0.211 0.332 0.401 0.091 0.105 0.415
p value <0.001 <0.001 < 0.001 < 0.001 < 0.001 < 0.001 0.003 0.002 <0.001
Transferrin/Cr 0.012 0.016 0.400 0.041 0.079 0.126 0.035 0.028 0.335
p value 0.058 0.044 <0.001 0.004 <0.001 <0.001 0.070 0.127 <0.001
RBP/Cr 0.044 0.076 0.409 0.081 0.127 0.196 0.058 0.061 0.391
p value <0.001 <0.001 < 0.001 < 0.001 < 0.001 < 0.001 0.023 0.028 <0.001
NGAL/Cr 0.053 0.051 0.361 0.019 0.020 0.059 0.134 0.135 0.427
p value <0.001 <0.001 < 0.001 0.053 0.061 0.003 <0.001 <0.001 <0.001
  1. Group 1, eGFR ≥60 mL/min/1.73 m2; Group 2, eGFR <60 mL/min/1.73 m2; ACR Albumin-to-creatinine ratio, PCR Total protein-to-creatinine ratio, Transferrin/Cr transferrin-to-creatinine ratio; RBP/Cr Retinol binding protein-to-creatinine ratio, NGAL/Cr Neutrophil gelatinase-associated lipocalin-to-creatinine ratio
  2. Model 1, adjusted for age, gender and duration of diabetes
  3. Model 2, adjusted for age, gender and duration of diabetes, SBP
  4. Model 3, adjusted for age, gender, duration of diabetes, SBP, HbA1c, LDL and eGFR
  5. Values of p < 0.05 were considered significant