Table 2 Baseline characteristics of subjects by quartiles of TC

Age (Years)

38(18)

46(22)^*

50(23)^*#

55(21)^*#※

< 0.001

Male (%)

833(63.4)

809(62.9)^*

800(61.9)^*#

734(56.9)^*#※

< 0.001

BMI (kg/m²)

22.54 ± 2.95

23.12 ± 2.94^*

23.48 ± 2.95^*#

23.84 ± 3.11^*#※

< 0.001

Overweight (24 ≤ BMI < 28) (%)

340(25.9)

418(32.5)^*

471(36.5)^*#

502(38.9)^*#※

< 0.001

Obesity (BMI ≥ 28) (%)

56(4.3)

64(5.0)^*

77(6.0)^*#

114(8.8)^*#※

< 0.001

SBP (mmHg)

120.27 ± 16.71

124.36 ± 17.67^*

126.50 ± 18.83^*#

130.88 ± 19.42^*#※

< 0.001

DBP (mmHg)

72.52 ± 10.58

74.97 ± 11.25^*

76.33 ± 11.38^*#

78.45 ± 11.24^*#※

< 0.001

TG (mmol/L)

1.08 ± 0.76

1.28 ± 0.85^*

1.49 ± 0.96^*#

1.87 ± 1.27^*#※

< 0.001

HDL-C (mmol/L)

1.37 ± 0.34

1.32 ± 0.30^*

1.29 ± 0.29^*#

1.21 ± 0.25^*#※

< 0.001

LDL-C (mmol/L)

2.03 ± 0.38

2.55 ± 0.34^*

2.98 ± 0.37^*#

3.67 ± 0.67^*#※

< 0.001

BUN (mmol/L)

4.79 ± 1.07

4.98 ± 1.13^*

5.07 ± 1.19^*#

5.15 ± 1.13^*#※

< 0.001

FPG (mmol/L)

5.08 ± 0.65

5.20 ± 0.81^*

5.26 ± 0.80^*#

5.41 ± 0.99^*#※

< 0.001

SCr (μmol/L)

82.26 ± 13.48

82.75 ± 13.91

83.03 ± 13.61^*

83.13 ± 13.88^*#

0.371

SUA (mg/dl)

5.44 ± 1.28

5.56 ± 1.32^*

5.65 ± 1.36^*#

5.83 ± 1.39^*#※

< 0.001

Hypertension (%)

131(10.0)

192(14.9)^*

227(17.6)^*#

299(23.1)^*#※

< 0.001

Diabetes (%)

42(3.2)

53(4.0)^*

41(3.2)^#

62(4.8)^*#※

0.089

eGFR (ml/min/1.73m²)

90.81 ± 15.67

87.60 ± 16.09^*

84.84 ± 14.35^*#

81.56 ± 13.40^*#※

< 0.001

New incident CKD (%)

27(2.1)

54(4.2)^*

43(3.3)^*#

103(8.0)^*#※

< 0.001