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Table 5 Univariate and multivariate Cox-proportional hazard analysis of variables associated with all-cause mortality

From: Comparison of clinical features and outcomes between patients with early and delayed lupus nephritis

Ā 

Univariate analysis

Multivariate analysis

Odds ratio

95% CI

p-value

Odds ratio

95% CI

p-value

Age, years

1.066

1.019ā€“1.115

0.006

1.065

1.018ā€“1.114

0.006

Female sex

1.117

0.141ā€“8.851

0.917

Ā Ā Ā 

SLEDAI-2ā€‰K

0.927

0.782ā€“1.099

0.382

Ā Ā Ā 

Complement 3, mg/dL

0.990

0.963ā€“1.017

0.443

Ā Ā Ā 

Complement 4, mg/dL

0.924

0.814ā€“1.048

0.220

Ā Ā Ā 

Anti-dsDNA (IU/mL)

0.998

0.995ā€“1.002

0.314

Ā Ā Ā 

Spot urine P/Cr ratio

0.682

0.458ā€“1.017

0.060

Ā Ā Ā 

WBC count (/Ī¼L)

1.000

0.999ā€“1.000

0.445

Ā Ā Ā 

Platelet count (Ɨ1000/Ī¼L)

1.000

0.993ā€“1.007

0.996

Ā Ā Ā 

Hemoglobin (g/dL)

0.653

0.467ā€“0.913

0.013

0.656

0.448ā€“0.959

0.030

Lymphocyte count (/Ī¼L)

0.999

0.998ā€“1.001

0.361

Ā Ā Ā 

ESR (mm/hr)

1.010

0.991ā€“1.029

0.323

Ā Ā Ā 

CRP (mg/L)

1.017

1.001ā€“1.033

0.034

Ā Ā Ā 

Cr (mg/dL)

1.479

0.889ā€“2.461

0.132

Ā Ā Ā 

Albumin (g/dL)

0.927

0.399ā€“2.152

0.860

Ā Ā Ā 

Activity index

1.004

0.892ā€“1.129

0.954

Ā Ā Ā 

Chronicity index

1.233

0.861ā€“1.766

0.252

Ā Ā Ā 

Early lupus nephritis

0.671

0.194ā€“2.319

0.529

Ā Ā Ā 

Delayed lupus nephritis

1.490

0.431ā€“5.148

0.529

Ā Ā Ā 

Hypertension

2.965

0.834ā€“10.539

0.093

Ā Ā Ā 

Diabetes mellitusa

n/a

Ā Ā Ā 

Dyslipidemiaa

n/a

Ā Ā Ā 
  1. SLEDAI-2ā€‰K systemic lupus erythematosus disease activity index-2000, P/Cr protein/creatinine, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, Cr creatinine, n/a not applicable
  2. aThe odds ratio was not calculable because no death occurred in patients with diabetes mellitus and dyslipidaemia