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Table 4 Multivariate Cox proportional hazard model for all-cause mortality

From: Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients

Variables

Model 1

Model 2

Hazard Ratio (95% CI)

P value

Hazard Ratio (95% CI)

P value

T cell count (cells/μl)

0.325 (0.146, 0.719)

0.006

  

Naïve T cell count (cells/μl)

0.042 (0.004, 0.429)

0.008

0.030 (0.004, 0.247)

0.001

 

CD4+naïve T cell count (cells/μl)

0.031 (0.002, 0.496)

0.014

  

CD8+naïve T cell count (cells/μl)

0.000 (0.000, 1.133)

0.053

  

T cell (%)

0.080 (0.014, 0.445)

0.004

  

CD8+central-memory T cell (%)

2.261 (1.092, 4.681)

0.028

  

CD8+effector-memory T cell (%)

4.946 (0.849, 28.827)

0.075

  

CD8+EMRA T cell (%)

0.251 (0.063, 1.008)

0.051

  
  1. Backward conditional method was used. Model 1 included each T cell parameters and was adjusted for age, sex, BMI, history of CVD, history of diabetes, dialysis duration, hemoglobin, albumin, prealbumin, urea nitrogen, creatinine, uric acid, phosphorus, calcium, intact parathyroid hormone, β2-microglobulin, homocysteine, soluble interleukin-2 receptor, N-terminal pro-brain natriuretic peptide and high-sensitivity C-reactive protein. Model 2 included all the related T cell parameters and was adjusted for the same factors as model 1