Fig. 4

Micrographs showing various forms of calcification seen in CKD/ESKD (Fig. a-e) and control patient (Fig. f). Von Kossa staining shows (a) Vessels < 50 μm in diameter with granular and circumferential medial calcification in subcutaneous tissue and higher magnification insert of vessels highlighted in black box from Panel A. b Vessel 100 μm in diameter with granular calcification throughout the media and alongside the internal elastic lamina in subcutaneous tissue and higher magnification of vessel highlighted in black box from Panel B (c) Vessel 100 μm in diameter with granular medial calcification in dermal tissue; d Confluent internal elastic lamina calcification of vessel > 100 μm in diameter in subcutaneous tissue; e Perieccrine calcification in dermal tissue; f Subtle and stippled calcification of vessel > 100 μm in diameter in control patient. All photos taken at 20x magnification. Scale bar denoted in each panel