Vascular calcification in skin and subcutaneous tissue in patients with chronic and end-stage kidney disease

BMC Nephrology

Table 1 Clinical features of study cohort

Demographics	CKD (n = 34)	Control (n = 11)	P value
Age, years	60 ± 16	62 ± 9	0.3
Gender, male	22 (69%)	4 (36%)
BMI (kg/m²)	27 [24–33]	27 [24–31]	0.8
Dialysis modality	26 HD, 5 PD, 3 CKD	n/a
Time on dialysis (years)	4 [2.8–9.8]
Comorbidities
Smoker (current)	5 (15%)	2 (18%)	0.6
Smoker (former)	13 (38%)	2 (18%)	0.8
Diabetes	13 (38%)	2 (18%)	0.8
Hypertension	24 (70%)	2 (18%)	0.7
IHD	7 (20%)	0
PVD	4 (12%)	0
Parathyroidectomy	4 (12%)	0
Biochemical parameters
Corrected calcium (mmol/L)	2.3 ± 0.2	2.3 ± 0.2	0.65
Phosphate (mmol/L)	1.9 ± 0.6	1.1 ± 0.2	0.002
ALP (IU/L)	107 [81–149]	74 [64–102]	0.03
PTH (pmol/L)	62 [37–148]	4.6 [0.9–8]	< 0.001

Results are mean ± SD, median [IQR] or number (%)
Abbreviations: ALP alkaline phosphatase, BMI body mass index, HD haemodialysis, IHD ischaemic heart disease, PD peritoneal dialysis, PTH parathyroid hormone, PVD peripheral vascular disease

ISSN: 1471-2369