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Table 3 Differences between CKD/ESKD participants with and without VC

From: Vascular calcification in skin and subcutaneous tissue in patients with chronic and end-stage kidney disease

Demographic features

VC present (n = 13)

VC absent (n = 21)

P value

Age, years

57 ± 13

59 ± 18

0.60

Sex (male)

8 (61%)

17 (80%)

0.21

BMI (kg/m2)

27 ± 4

29 ± 6

0.24

Time on dialysis (if ESKD), years

2.5 [1.77–6]

4.2 [2–6.5]

0.25

CKD stage

 Pre-dialysis

1 (eGFR 17 ml/min2)

2 (mean eGFR 20 ± 0.7 ml/min2)

 

 PD

4

1

 

 HD

8 (57%)

18 (86%)

 

Diabetes

4 (30%)

9 (42%)

0.55

Hypertension

10 (77%)

14 (67%)

0.52

IHD

3 (23%)

4 (19%)

0.78

PVD

1 (7%)

3 (14%)

0.56

Smoker (current or former)

8 (57%)

15 (50%)

0.66

Previous parathyroidectomy

2 (15%)

2 (9%)

0.64

Calcitriol use

7 (50%)

10 (34%)

0.24

Non-calcium-based binder

7 (50%)

11 (38%)

0.35

Calcium based binder

2 (15%)

10 (47%)

0.06

PTH, pmol/L

58 [37–184]

66 [37–123]

0.41

Total calcium, mmol/L

2.3 ± 0.2

2.4 ± 0.2

0.57

Phosphate, mmol/L

2 ± 0.5

1.9 ± 0.7

0.71

ALP, IU/L

106 [76–207]

108 [81–139]

0.72

Vessel number

44 ± 19

39 ± 15

0.91

Perieccrine calcification

9 (69%)

4 (19%)

0.003

  1. Results are mean ± SD, median [IQR] or number (%)
  2. Abbreviations: ALP alkaline phosphatase, BMI body mass index, HD haemodialysis, IHD ischaemic heart disease, PD peritoneal dialysis, PTH parathyroid hormone, PVD peripheral vascular disease