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Table 4 Factors for predicting increased oxidative stress (protein carbonyl ≥ Q4)

From: Serum levels of protein carbonyl, a marker of oxidative stress, are associated with overhydration, sarcopenia and mortality in hemodialysis patients

Variables Univariate Multivariate
OR (95% CI) P value OR (95% CI) P value
Diabetes 0.54 (0.21–1.4) 0.217 0.45 (0.15–1.37) 0.157
CAD 2.62 (0.95–7.26) 0.064 2.45 (0.78–7.73) 0.127
CVD 1.86 (0.63–5.48) 0.262 1.53 (0.44–5.32) 0.506
Dialysis vintage 1.00 (0.99–1.02) 0.283 1.01 (0.99–1.02) 0.439
β2-microglobulin 1.02 (0.96–1.09) 0.485 1.01 (0.94–1.09) 0.740
Albumin 0.48 (0.14–1.70) 0.256 0.45 (0.10–2.02) 0.299
Prealbumin* 0.91 (0.85–0.98) 0.009 0.91 (0.83–0.99) 0.030
hs-CRP (log units) 1.32 (0.91–1.92) 0.150 1.51 (0.97–2.33) 0.066
Overhydration* 4.13 (1.32–12.96) 0.015 7.01 (1.77–27.79) 0.006
SGA (B vs. A)* 3.75 (1.32–10.68) 0.013 3.52 (1.08–11.46) 0.037
Low HGS 2.67 (0.93–7.66) 0.068 3.65 (0.99–13.51) 0.052
Low LTI* 3.50 (1.28–9.59) 0.015 4.63 (1.40–15.29) 0.012
Sarcopenia* 2.16 90.78–6.00) 0.138 3.41 (1.02–11.32) 0.046
  1. Multivariate logistic analysis was performed after adjusting for age, gender, body mass index, diabetes, coronary artery disease, cerebrovascular disease, dialysis vintage
  2. CAD coronary artery disease, CVD cerebrovascular disease, hs-CRP high-sensitivity C-reactive protein, SGA subjective global assessment, HGS handgrip strength, LTI lean tissue index
  3. *p < 0.05