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Table 4 Factors for predicting increased oxidative stress (protein carbonyl ≥ Q4)

From: Serum levels of protein carbonyl, a marker of oxidative stress, are associated with overhydration, sarcopenia and mortality in hemodialysis patients

Variables

Univariate

Multivariate

OR (95% CI)

P value

OR (95% CI)

P value

Diabetes

0.54 (0.21–1.4)

0.217

0.45 (0.15–1.37)

0.157

CAD

2.62 (0.95–7.26)

0.064

2.45 (0.78–7.73)

0.127

CVD

1.86 (0.63–5.48)

0.262

1.53 (0.44–5.32)

0.506

Dialysis vintage

1.00 (0.99–1.02)

0.283

1.01 (0.99–1.02)

0.439

β2-microglobulin

1.02 (0.96–1.09)

0.485

1.01 (0.94–1.09)

0.740

Albumin

0.48 (0.14–1.70)

0.256

0.45 (0.10–2.02)

0.299

Prealbumin*

0.91 (0.85–0.98)

0.009

0.91 (0.83–0.99)

0.030

hs-CRP (log units)

1.32 (0.91–1.92)

0.150

1.51 (0.97–2.33)

0.066

Overhydration*

4.13 (1.32–12.96)

0.015

7.01 (1.77–27.79)

0.006

SGA (B vs. A)*

3.75 (1.32–10.68)

0.013

3.52 (1.08–11.46)

0.037

Low HGS

2.67 (0.93–7.66)

0.068

3.65 (0.99–13.51)

0.052

Low LTI*

3.50 (1.28–9.59)

0.015

4.63 (1.40–15.29)

0.012

Sarcopenia*

2.16 90.78–6.00)

0.138

3.41 (1.02–11.32)

0.046

  1. Multivariate logistic analysis was performed after adjusting for age, gender, body mass index, diabetes, coronary artery disease, cerebrovascular disease, dialysis vintage
  2. CAD coronary artery disease, CVD cerebrovascular disease, hs-CRP high-sensitivity C-reactive protein, SGA subjective global assessment, HGS handgrip strength, LTI lean tissue index
  3. *p < 0.05
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BMC Nephrology

ISSN: 1471-2369

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