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Table 1 Neonatal KDIGO (Kidney Diseases: Improving Global Outcomes) acute kidney injury definition

From: Clinical effect and safety of continuous renal replacement therapy in the treatment of neonatal sepsis-related acute kidney injury

Stage Serum creatinine (SCr) Urine output over 24 h
0 No change in serum creatinine or rise < 0.3 mg/dL > 1 mL/kg/h
1
2
3
SCr rise ≥0.3 mg/dL within 48 h or
SCr rise ≥1.5 to 1.9 × reference SCr a within 7 days
SCr rise ≥2 to 2.9 × reference SCr a
SCr rise ≥3 × reference SCr a or SCr ≥2.5 mg/dL a or Receipt of dialysis
> 0.5 and ≤ 1 mL/kg/h
> 0.3 and ≤ 0.5 mL/kg/h
≤0.3 mL/kg/h
  1. a Reference SCr is the lowest prior SCr measurement