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Table 1 Neonatal KDIGO (Kidney Diseases: Improving Global Outcomes) acute kidney injury definition

From: Clinical effect and safety of continuous renal replacement therapy in the treatment of neonatal sepsis-related acute kidney injury

Stage

Serum creatinine (SCr)

Urine output over 24 h

0

No change in serum creatinine or rise < 0.3 mg/dL

> 1 mL/kg/h

1

2

3

SCr rise ≥0.3 mg/dL within 48 h or

SCr rise ≥1.5 to 1.9 × reference SCr a within 7 days

SCr rise ≥2 to 2.9 × reference SCr a

SCr rise ≥3 × reference SCr a or SCr ≥2.5 mg/dL a or Receipt of dialysis

> 0.5 and ≤ 1 mL/kg/h

> 0.3 and ≤ 0.5 mL/kg/h

≤0.3 mL/kg/h

  1. a Reference SCr is the lowest prior SCr measurement