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Table 5 Biology-derived Biomarkers

From: Mannitol and renal graft injury in patients undergoing deceased donor renal transplantation – a randomized controlled clinical trial

 

Mannitol

(n = 16)

Placebo

(n = 16)

p-value

MMP1

3492 [3040, 4910]

3828 [3299, 6556]

0.360

CHI3L1

277,789 ± 119,127

290,668 ± 43,544

0.882

CCL2

244 [208, 314]

240 [196, 303]

0.711

MMP8

17,414 ± 11,898

13,001 ± 7340

0.126

HGF

1488 ± 847

1736 ± 1124

0.800

GH

286 [189, 598]

511 [292, 981]

0.387

FGF23

170 [67, 1673]

215 [116, 722]

0.183

Tie2

12,563 [9594, 18,103]

16,357 [14,596, 20,411]

0.011

VCAM1

2,057,315 [1,483,384, 3,106,136]

1,741,057 [1,422,526, 2,331,264]

0.354

TNFR1

36,465 ± 14,344

32,838 ± 10,274

0.272

IGFBP7

19,960 ± 4097

19,385 ± 2886

0.556

IL18

158 [130, 208]

221 [171, 304]

0.202

NGAL

252,684 [202,155, 340,047]

206,354 [182,217, 273,962]

0.091

Endostatin

314,261 ± 123,046

307,918 ± 74,018

0.981

CystC

2,405,546 [1,716,719, 2,976,273]

2,023,359 [1,794,789, 2,449,441]

0.994

KIM1

249 ± 197

227 ± 108

0.624

  1. Testing for differences in BM concentrations 24 h after transplantation. Data are presented as means ±SD or medians [25th percentile, 75th percentile]. All concentrations are given in pg/mL A mixed linear model adjusted for paired donor kidneys was applied
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BMC Nephrology

ISSN: 1471-2369

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