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Fig. 1 | BMC Nephrology

Fig. 1

From: An unusual presentation of propylthiouracil-induced anti-MPO and PR3 positive ANCA vasculitis with associated anti-GBM antibodies, IgA nephropathy and an IgG4 interstitial infiltrate: a case report

Fig. 1

Histology from renal biopsy at 40x magnification (a-e). Segmental necrosis with rupture of glomerular tuft and Bowman’s capsule (a; Jones silver-H&E stain). Large cellular crescent (b; Jones silver-H&E stain). Plasma cell rich tubulointerstitial infiltrate (c; H&E stain). Tubulointerstitial infiltrate rich in IgG4-positive cells (d; IgG4 immunohistochemical staining, IgG4-positive cells stained brown). Predominantly mesangial distribution of IgA (e; Immunoperoxidase staining for IgA). Electron microscopy at 6000x magnification showing paramesangial electron dense deposits (f) and subendothelial deposits associated with endocapillary hypercellularity (g) typical of IgA nephropathy

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BMC Nephrology

ISSN: 1471-2369

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