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Table 3 Clinical parameters before and after treatment with OSCA

From: New oral spherical carbon adsorbent effectively reduces serum indoxyl sulfate levels in moderate to advanced chronic kidney disease patients: a multicenter, prospective, open-label study

  Before treatment (n = 87) After treatment (n = 87) P
Body weight (kg) 71.2 ± 13.9 70.6 ± 13.8 0.03
Systolic BP (mmHg) 131.2 ± 11.7 128.3 ± 16.1 0.06
Diastolic BP (mmHg) 79.0 ± 11.2 75.1 ± 11.2 0.01
Hemoglobin (g/dL) 12.1 ± 2.0 11.9 ± 1.9 0.04
Phosphorus (mg/dL) 3.6 ± 0.6 3.7 ± 0.7 0.07
Uric acid (mg/dL) 7.1 ± 1.8 7.3 ± 1.8 0.05
BUN (mg/dL) 35.2 ± 12.7 36.1 ± 12.7 0.37
Serum creatinine (mg/dL) 2.5 ± 0.8 2.6 ± 0.9 0.06
eGFR by Creatinine (mL/min/1.73m2) 31.7 ± 11.3 32.0 ± 13.1 0.57
Serum albumin (g/dL) 3.9 ± 0.6 3.9 ± 0.5 0.43
  1. The paired t-tests were performed to compare the two groups
  2. Abbreviation: OSCA oral spherical carbon adsorbent, BMI body mass index, BP blood pressure, CKD chronic kidney disease, eGFR estimated glomerular filtration rate
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