Outcomes (Number of Studies) | Events in kidney transplant patients | Events in non-transplanted patients | Certainty of evidence (GRADE) | Rationale | |||||
---|---|---|---|---|---|---|---|---|---|
Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | Strong association | ||||
30 day/In-hospital mortality (8) | 449/8151 | 79,978/3,272,453 | Low a,d,g,f | ↓ | – | – | – | – | ↑ |
Myocardial infarction (4) | 104/4793 | 55,029/3,088,295 | Very low a,b,c,g | ↓ | ↓↓ | – | ↓↓ | – | – |
Stroke (7) | 91/7636 | 54,508/4,794,679 | Very low a,b,c,g | ↓ | ↓↓ | – | ↓↓ | – | – |
Cardiac failure (3) | 1109/7129 | 126,004/1,848,386 | Very low a,c,g | ↓ | ↓↓ | – | – | – | – |
Surgical site infection (8) | 293/8360 | 85,747/3,536,106 | Very low a,b,c,g | ↓ | ↓↓ | – | ↓ | – | – |
Pneumonia (8) | 693/8151 | 196,982/3,272,453 | Very low a,c,g | ↓ | ↓↓ | – | – | – | – |
Sepsis (5) | 692/4019 | 15,951/164,139 | Low a,c,g,f | ↓ | – | – | – | – | ↑ |
Gastrointestinal events (6) | 495/8006 | 414,890/3,272,004 | Very lowa,c,g,h | ↓ | ↓↓ | – | ↓ | – | – |
Blood transfusion (5) | 2056/7505 | 424,174/3,087,470 | Very lowa,c,g,h | ↓ | ↓ | – | – | – | – |
Unplanned return to theatre (6) | 53/395 | 75/1524 | Very lowa,b,g | ↓ | ↓ | – | ↓↓ | – | – |
AKI (11) | 2205/15,371 | 316,667/7,807,595 | Moderate a,c,e,g | ↓ | ↓↓ | – | – | – | ↑↑ |
PE/DVT (3) | 204/4723 | 81,226/3,087,400 | Very low a,b,c,g | ↓ | ↓↓ | – | ↓↓ | – | – |