Table 1 Laboratory results. The days listed are in reference to the date of admission, which was also the date of first gentamicin exposure
Pre-admission | Day 0 16/9 | Day 1 | Day 2 | Day 4 | Day 5 | Day 7 | Day 9 | Day 11 | Day 13 | Day 14 | Day 16 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serum creatinine (μmol/L) (Reference range: 60-110) | 84 | 82 | 69 | 69 | 67 | 73 | 80 | 66 | 72 | 72 | 84 | 74 |
eGFR (mL/min/1.73m2) (Reference range: >60) | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 | > 90 |
Serum potassium (mmol/L) (Reference range: 3.5-5.2) | 4.2 | 3.9 | ↓ 3.0 | ↓ 3.0 | ↓ 3.1 | ↓ 3.3 | 4.2 | 4.6 | 4.6 | 4.7 | 4.3 | 4.3 |
Serum chloride (mmol/L) (Reference range: 95-110) | ↓90 | ↓87 | ↓88 | ↓93 | ↓87 | ↓87 | ↓90 | ↓88 | ↓ 90 | 95 | ↓ 94 | 96 |
Serum phosphate (mmol/L) (Reference range: 0.75-1.5) | 0.96 | 0.89 | ↓ 0.49 | ↓ 0.67 | ↓ 0.47 | ↓ 0.72 | ↓ 0.53 | ↓ 0.59 | ↓ 0.54 | 1.0 | 1.05 | 1.14 |
Serum magnesium (mmol/L) (Reference range: 0.7-1.1) | 0.77 | 0.60 | ↓0.51 | ↓0.52 | 0.84 | ↓0.62 | ↓0.69 | 0.87 | 0.71 | 0.74 | ↓0.65 | 0.70 |
Urine potassium (mmol/L) | 24 | 40 | ||||||||||
Fractional excretion of potassium | ↑ 21.5% | ↑ 24.6% | ||||||||||
Urine phosphate (mmol/L) | 8.0 | 6 | ||||||||||
Fractional excretion of phosphate | ↑ 60.5% | 13.9% | ||||||||||
Urine glucose (mmol/L) | ↑ 107 | ↑ 4.2 | 0.2 | |||||||||
Urine protein creatinine ratio (mg/mmol creatinine) (Reference range: <12) | ↑ 154 | ↑ 162 | ↑ 39.3 |