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Table 1 List of clinical information and biospecimens in the KORNERSTONE

From: Biobanking for glomerular diseases: a study design and protocol for KOrea Renal biobank NEtwoRk System TOward NExt-generation analysis (KORNERSTONE)

Parameters Detailed information Screening Baseline 1 Y 2 Y 3 Y 4 Y 5 Y Improvement or deterioration of clinical outcomes Hard outcomes (ESRD, CV outcomes)
Informed consent   O         
Demographic information   O         
Medical history   O         
Medications Hypertensive medications   O O O O O O O O
Immunosuppressant   O O O O O O O O
Questionnaires Health questionnaires (including smoking)   O O O O O O O O
KDQOL-SF version 1.3 questionnaires   O O O O O O O O
Semi-food frequency questionnaires   O O O O O O O O
PedsQL 4.0 Generic Core Scales (Children)   O        O
Anthropometry Height, weight   O O O O O O   O
Blood pressure   O O O O O O   O
Blood laboratory findings CBC (white blood cell count, platelet, haemoglobin)   O O O O O O O O
Chemistry (calcium, phosphorus, glucose, blood urea nitrogen, uric acid, total protein, albumin, total bilirubin, alkaline phosphatase, AST, ALT)   O O O O O O O O
IDMS-traceable Cr, eGFR   O O O O O O O O
Lipid panel (total cholesterol, triglyceride, high-density lipoprotein, low density lipoprotein)   O O O O O O O O
Electrolyte panel (sodium, potassium, chloride)   O O O O O O O O
Total CO2   O O O O O O O O
C-reactive protein   O O O O O O O O
Serology (HBsAg, HBsAb, Anti-HCV, HIV, VDRL)   O        
Anti-dsDNA, FANA, FANA titre, ANCA, PR3, MPO   O        
Complement 3, 4   O        
ASO, rheumatoid factor, Cryoglobulin   O        
Urine laboratory findings Random urine protein   O O O O O O O O
Random urine microalbumin   O O O O O O O O
Random urine creatinine   O O O O O O O O
Urinalysis protein   O O O O O O O O
Urinalysis RBC   O O O O O O O O
Kidney biopsy Biopsy results and images including LM, IF and EM   O        
Report of diagnosis   O        
Total number of glomeruli   O        
Total number of global sclerosis/segmental sclerosis/crescent   O        
Biospecimens Serum/plasma/buffy coat/genomic DNA sample   O O O O O O O O
Urine sample   O O O O O O O O
Stool sample   O        
cDNA from glomeruli and tubules in micro-dissected kidney biopsy tissues   O        
  1. CBC complete blood count; KDQOL-SF Kidney Disease-Quality of Life Short Form; PedsQL Pediatric Quality of Life Inventory; AST aspartate aminotransferase; ALT alanine aminotransferase; HCV hepatitis C virus; HIV human immunodeficiency virus; VDRL veneral disease research laboratory test; FANA fluorescent antinuclear antibody; MPO myeloperoxidase; ASO antistreptolysin O; RBC red blood cell; LM light microscopy; IF immunofluorescent; EM electron microscopy; IDMS isotope dilution mass spectrometry; Cr creatinine; eGFR estimated glomerular filtration rate; Y year
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