Table 1 List of clinical information and biospecimens in the KORNERSTONE

Informed consent

O

Demographic information

O

Medical history

O

Medications

Hypertensive medications

O

O

O

O

O

O

O

O

Immunosuppressant

O

O

O

O

O

O

O

O

Questionnaires

Health questionnaires (including smoking)

O

O

O

O

O

O

O

O

KDQOL-SF version 1.3 questionnaires

O

O

O

O

O

O

O

O

Semi-food frequency questionnaires

O

O

O

O

O

O

O

O

PedsQL 4.0 Generic Core Scales (Children)

O

O

Anthropometry

Height, weight

O

O

O

O

O

O

O

Blood pressure

O

O

O

O

O

O

O

Blood laboratory findings

CBC (white blood cell count, platelet, haemoglobin)

O

O

O

O

O

O

O

O

Chemistry (calcium, phosphorus, glucose, blood urea nitrogen, uric acid, total protein, albumin, total bilirubin, alkaline phosphatase, AST, ALT)

O

O

O

O

O

O

O

O

IDMS-traceable Cr, eGFR

O

O

O

O

O

O

O

O

Lipid panel (total cholesterol, triglyceride, high-density lipoprotein, low density lipoprotein)

O

O

O

O

O

O

O

O

Electrolyte panel (sodium, potassium, chloride)

O

O

O

O

O

O

O

O

Total CO₂

O

O

O

O

O

O

O

O

C-reactive protein

O

O

O

O

O

O

O

O

Serology (HBsAg, HBsAb, Anti-HCV, HIV, VDRL)

O

Anti-dsDNA, FANA, FANA titre, ANCA, PR3, MPO

O

Complement 3, 4

O

ASO, rheumatoid factor, Cryoglobulin

O

Urine laboratory findings

Random urine protein

O

O

O

O

O

O

O

O

Random urine microalbumin

O

O

O

O

O

O

O

O

Random urine creatinine

O

O

O

O

O

O

O

O

Urinalysis protein

O

O

O

O

O

O

O

O

Urinalysis RBC

O

O

O

O

O

O

O

O

Kidney biopsy

Biopsy results and images including LM, IF and EM

O

Report of diagnosis

O

Total number of glomeruli

O

Total number of global sclerosis/segmental sclerosis/crescent

O

Biospecimens

Serum/plasma/buffy coat/genomic DNA sample

O

O

O

O

O

O

O

O

Urine sample

O

O

O

O

O

O

O

O

Stool sample

O

cDNA from glomeruli and tubules in micro-dissected kidney biopsy tissues

O