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Table 3 Diagnostic test parameters for urine neutrophil gelatinase-associated lipocalin (uNGAL) and urine output at different time points

From: Urine neutrophil gelatinase-associated lipocalin and urine output as predictors of the successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

  Urine output 24 h prior to discontinuation Urine output 6 h Urine output 12 h Urine output 24 h after discontinua-tion uNGAL at discontinuation uNGAL 6 h after discontinuation
(OUC24pre) (OUA6) (OUA12) (OUC24post) uNGAL 0 h uNGAL 6 h
AUC 0.86 0.89 0.92 0.84 0.80 0.81
Sensitivity 0.91 0.67 0.72 0.76 0.86 0.86
Specicificity 0.77 0.91 1.00 0.86 0.68 0.73
NPV 0.85 0.67 0.73 0.76 0.79 0.80
PPV 0.85 0.91 1.00 0.86 0.77 0.81
Cut-off, You-den’s index 210 ml 18 ml 24 ml 1260 ml 2403 μg/L 1650 μg/L
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