Urine neutrophil gelatinase-associated lipocalin and urine output as predictors of the successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

Table 3 Diagnostic test parameters for urine neutrophil gelatinase-associated lipocalin (uNGAL) and urine output at different time points

	Urine output 24 h prior to discontinuation	Urine output 6 h	Urine output 12 h	Urine output 24 h after discontinua-tion	uNGAL at discontinuation	uNGAL 6 h after discontinuation
	(OUC24pre)	(OUA6)	(OUA12)	(OUC24post)	uNGAL 0 h	uNGAL 6 h
AUC	0.86	0.89	0.92	0.84	0.80	0.81
Sensitivity	0.91	0.67	0.72	0.76	0.86	0.86
Specicificity	0.77	0.91	1.00	0.86	0.68	0.73
NPV	0.85	0.67	0.73	0.76	0.79	0.80
PPV	0.85	0.91	1.00	0.86	0.77	0.81
Cut-off, You-den’s index	210 ml	18 ml	24 ml	1260 ml	2403 μg/L	1650 μg/L

ISSN: 1471-2369