Table 3 Associated factors of uric acid clearance on hemodialysis in ESKD
Variables | Uric acid Clearance | p-value | OR [95% CI] | |
|---|---|---|---|---|
≥ 65% | < 65% | |||
N (%) | 94 (100) | 50 (100) | ||
Age, n (%) | ||||
< 50 years | 47 (50) | 26 (52) | 0.8 | – |
≥ 50 years | 47 (50) | 24 (48) | ||
Sex, n (%) | ||||
Men | 56 (59.6) | 35 (70) | 0.2 | – |
Women | 38 (40.4) | 15 (30) | ||
Comorbidities | ||||
Excess weight, n (%) | ||||
Yes | 25 (26.6) | 22 (44) | 0.03 | 0.4 [0.2; 0.9] |
No | 69 (73.4) | 28 (56) | ||
Hypertension, n (%) | ||||
Yes | 84 (89.4) | 44 (88) | 0.8 | – |
No | 10 (10.6) | 6 (12) | ||
Diabetes, n (%) | ||||
Yes | 20 (21.3) | 13 (26) | 0.5 | – |
No | 74 (78.7) | 37 (74) | ||
Gout, n (%) | ||||
Yes | 8 (8.5) | 8 (16) | 0.1 | – |
No | 86 (91.5) | 42 (84) | ||
Underlying nephropathy | ||||
Hypertensive nephropathy, n (%) | ||||
Yes | 57 (60.6) | 31 (62) | 0.8 | – |
No | 37 (39.4) | 19 (38) | ||
Diabetic nephropathy, n (%) | ||||
Yes | 80 (85.1) | 39 (78) | 0.2 | – |
No | 14 (14.9) | 11 (22) | ||
Chronic glomerulonephritis, n (%) | ||||
Yes | 80 (85.1) | 41 (82) | 0.6 | – |
No | 14 (14.9) | 9 (18) | ||
Hemodialysis related variables | ||||
Blood efflux, n (%) | ||||
< 300 ml/min | 49 (52.1) | 26 (52) | 0.9 | – |
> 300 ml/min | 45 (47.9) | 24 (48) | ||
Interval between dialytic sessions, n (%) | ||||
< 3 days | 16 (17) | 8 (16) | 0.8 | – |
≥ 3 days | 78 (83) | 42 (84) | ||
Size of the dialysis membrane, n (%) | ||||
FX 10 | 67 (71.3) | 38 (76) | 0.5 | – |
FX 8 or FX 5 | 27 (28.7) | 12 (24) | ||
Kt/Vurea | ||||
< 1.2 | 22 (23.4) | 38 (76) | 0.01 | 0.1 [0.04; 0.2] |
≥ 1.2 | 72 (76.6) | 12 (24) | ||