Fig. 1
From: NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis
NR1 was overexpressed in UUO-injured kidneys in C57BL/6 mice. a Western blots of the expression of NR1 in the control (Con) group, NR1-targeting shRNA-transfected (NR1-sh) group, UUO group, and UUO + NR1-sh group (A1) and band analysis (A2). b Immunohistochemical staining of the expression of NR1 in the Con group, UUO group, UUO + NR1-sh group, and UUO + Scr-sh group (n = 6). ***P < 0.001 versus the Con group; ##P < 0.01, ###P < 0.001 versus the NR1-sh group; △△△P < 0.001 versus the UUO group. Representative images from each group (original magnification: × 200; scale bar = 100 μm)