Fig. 6
From: NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis
Oral NMDAR inhibitor dextromethorphan protected kidneys from chronic RF after IR injury. a Injured kidneys on the left and healthy kidneys on the right, with Masson’s staining of injured kidneys. b Quantitative analysis of fibrosis, serum creatinine (SCr), blood urea nitrogen (BUN), and volume ratios of right/left kidneys. IR group, ischemia–reperfusion group; LD group, low-dose DXM-treated group; MD group, moderate-dose DXM-treated group; HD group, high-dose DXM-treated group. Representative image of n = 6 individual samples per group. The original magnification of images was 40× (scale bar = 100 μm)