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Table 1 Comparison of clinical characteristics between Malaysian renal transplant recipients who developed NODAT and those without NODAT at 1-year post- transplant

From: Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia

 

All patients

(n = 168)

N (%) or

mean ± SD

NODAT (n = 29)

N (%) or mean ± SD

NON-NODAT (n = 139)

N (%) or

mean ± SD

p

Gender

   

0.70

 - Male

98 (58)

16 (6)

82 (84)

 

 - Female

70 (42)

13 (19)

57 (81)

 

Age at transplant

34.8 (12.1)

39.3 ± 13.4

33.9 ± 11.8

0.03

Ethnicities

   

0.84

 - Malay

34 (20)

5 (15)

29 (85)

 

 - Chinese

115 (69)

20 (17)

95 (83)

 

 - Indian

19 (11)

4 (11)

15 (79)

 

Primary kidney disease

   

0.20

 - Glomerulonephritis

51 (30)

9 (18)

42 (82)

 

 - Hypertension

19 (11)

6 (32)

13 (68)

 

 - Others

98 (59)

14 (14)

84 (86)

 

Type of donor

   

0.76

 - Living related

71 (45)

11 (15)

60 (85)

 

 - Living non-related

20 (42)

3 (15)

17 (85)

 

 - Cadaveric

77 (12)

15 (20)

62 (80)

 

Place of transplant

   

0.05

 - Local

114 (67)

15 (13)

98 (87)

 

 - Overseas

54 (32)

14 (26)

40 (74)

 

Types of calcineurin inhibitors

   

0.66

 - Cyclosporine

90 (54)

15 (17)

75 (83)

 

 - Tacrolimus

67 (40)

11 (16)

56 (84)

 

 - Both

11 (6)

3 (27)

8 (73)

 

Duration of dialysis (month)

33.0 (40.5)

23.1 ± 23.5

35.5 ± 43.3

0.09

BMI (kg/m2)

21.3 (4.6)

21.9 ± 4.6

21.1 ± 4.4

0.35

Levels of creatinine (μmol/L)

127 (122.6)

112.24 ± 34.2

130.11 ± 99.1

0.68

Fasting blood glucose (μmol/L)

5.5 (1.4)

6.5 ± 1.8

5.2 ± 0.7

< 0.0001

Average daily dose of cyclosporine (mg/kg)

295.4 (116.5)

328.8 ± 125.8

280.6 ± 92.3

0.15

Average daily dose of tacrolimus (mg/day)

7.5 (3.4)

7.5 ± 3.1

7.8 ± 2.4

0.55

Average daily dose of prednisolone (mg/day)

15.8 (4.4)

16.2 ± 2.6

15.8 ± 2.6

0.45