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Table 3 Comparison of parameters between patients who developed CKD stage 3 vs those who did not develop CKD stage 3

From: Identifying risk factors for chronic kidney disease stage 3 in adults with acquired solitary kidney from unilateral nephrectomy: a retrospective cohort study

  Did not develop CKD stage 3 Developed CKD stage 3 Z/c2 P
n = 81 n = 91
Sex Male 54 (66.7%) 56 (61.5%) 0.489 0.484
Female 27 (33.3%) 35 (38.6%)
Age (years)   52 (45–61) 62 (52–70) −4.026 < 0.001
Duration after nephrectomy (years)   4 (3–13) 6 (2–15) −0.947 0.344
Serum creatinine (μmol/L)   89 (72–104) 145 (117–330) −9.761 < 0.001
eGFR (ml/min/1.73 m2)   81.9 ± 13.7 31.2 ± 19.7 −11.306 < 0.001
Kidney location Left 38 (46.9%) 51 (56.0%) 1.349 0.245
Right 43 (53.1%) 40 (44.0%)
Cause of ASK Tumors 47 (58%) 25 (27.5%) 25.407 < 0.001
Tuberculosis 10 (12.3%) 40 (44%)  
Trauma 4 (4.9%) 3 (3.3%)  
Other 6 (7.4%) 10 (11%)  
Unknown 14 (17.3%) 13 (14.3%)  
Current smoker No 63 (77.8%) 69 (75.8%) 0.092 0.762
Yes 18 (22.2%) 22 (24.2%)
History of CVD No 73 (90.1%) 60 (65.9%) 14.302 < 0.001
Yes 8 (9.9%) 31 (34.1%)
Hypertension No 42 (52.5%) 38 (43.2%) 1.459 0.227
Yes 38 (47.5%) 50 (56.8%)
Obesity No 50 (69.4%) 53 (63.9%) 0.54 0.462
Yes 22 (30.6%) 30 (36.1%)
Diabetes No 67 (88.2%) 51 (59.3%) 18.847 < 0.001
Yes 9 (11.8%) 35 (40.7%)
Hyperuricemia No 62 (77.5%) 48 (53.9%) 10.298 0.001
Yes 18 (22.5%) 41 (46.1%)
Dyslipidemia No 54 (77.5%) 71 (88.8%) 1.411 0.235
yes 12 (22.5%) 9 (11.2%)
  1. Note: Results are presented as numbers (percentages), medians (interquartile range), or medians (standard deviation); eGFR estimated glomerular filtration rate, ASK acquired solitary kidney, CVD cardiovascular disease
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