Fig. 4
From: Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases
Cytoskeleton-associated proteins were protected by saxagliptin after podocyte injuries by ADR. a In the control and ADR + saxagliptin group, synaptopodin and stress fibers were observed in the cytoplasm. In the ADR group, synaptopodin and stress fibers were not observed in the cytoplasm. b Area of synaptopodin/cell and stress fibers/cell in the saxagliptin group was maintained compared to that in the ADR group. c Levels of synaptopodin and RhoA in the ADR group was significantly lower than that in the control and ADR + saxagliptin group. *: P < 0.05, ***: P < 0.001