Fig. 2
Overview of approaches used to evaluate estimates of baseline serum creatinine. a Overview of GFR-based and direct SCr-based methods to estimate baseline serum creatinine (bSCr) in community children. Linear regression models using the height and age of community children were used for direct estimation of ebSCrheightCC and ebSCrageCC. b The estimated bSCr and measured SCr were compared in community children to evaluate the bias, precision and accuracy of methods. c AKI was defined in children with severe malaria using the different approaches to estimate bSCr, and the relationship between AKI and mortality was evaluated