Changes in 3-month mineral and bone disorder patterns were associated with all-cause mortality in prevalent hemodialysis patients with secondary hyperparathyroidism

Table 1 Baseline characteristics of the study population

Variable	Value
Demographics
Age, years	63 (55–71)
Sex, female, %	37.7
Body mass index, kg/m²	20.9 (19.0–23.3)
Cause of end-stage kidney disease, %
Glomerulonephritis	45.1
Diabetic nephropathy	24.2
Other disease	30.7
Comorbidities, %
Diabetes mellitus	31.6
Cardiovascular disease	60.0
Lung disease	7.4
Liver disease	14.1
Malignancy	5.1
Dialysis
Duration of dialysis, years	8.3 (3.7–14.3)
Kt/V, single pool	1.4 (1.2–1.6)
Dialysate Ca, %
< 3.0 mEq/L	52.0
≥ 3.0 mEq/L	48.0
Laboratory data
Serum albumin, g/dL	3.8 (3.5–4.0)
Blood hemoglobin, g/dL	10.5 (9.8–11.2)
MBD-related characteristics
Serum parameters
Ca, mg/dL^a	9.4 (8.9–10.1)
P, mg/dL	5.5 (4.6–6.3)
iPTH, pg/mL	267 (197–401)
History of parathyroidectomy, %	6.2
Prescription of MBD-related agents, %
VDRA	77.6
Intravenous	48.4
Oral	30.4
Phosphate binder	85.1
Ca carbonate	66.7
Sevelamer hydrochloride	41.1
Cinacalcet hydrochloride^b	0.0

Data were derived from the subcohort (n = 3276) randomly selected from the study population
Continuous variables were expressed as median (interquartile range)
iPTH Intact parathyroid hormone, Ca Calcium, MBD Mineral and bone disorder, P Phosphorus, VDRA Vitamin D receptor activator
^aAlbumin-corrected value; calcium + (4.0—albumin), if albumin is less than 4.0 g/dL
^bBecame available in January 2008 in Japan

ISSN: 1471-2369