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Table 3 Outcomes following DEB of patients who underwent percutaneous coronary intervention with drug-eluting balloons

From: Cardiovascular outcomes following percutaneous coronary intervention with drug-eluting balloons in chronic kidney disease: a retrospective analysis

 

Full cohort

In-stent restenosis

De-novo lesions

Variable

All patients

Non-CKD

CKD

P value

All patients

Non-CKD

CKD

P value

All patients

Non-CKD

CKD

P value

Patients (n)

362

261

101

 

101

65

36

 

261

196

65

 

MACE- 1st year (%)

60 (16.6%)

36 (13.8%)

24 (23.8%)

< 0.05

25 (24.8%)

11 (16.9%)

14 (38.9%)

< 0.05

35 (13.4%)

25 (12.8%)

10 (15.4%)

0.7

MI- 1st year (%)

26 (7.2%)

10 (3.8%)

16 (15.9%)

< 0.001

16 (15.85%)

5 (7.7%)

11 (30.6%)

< 0.01

10 (3.8%)

5 (2.6%)

5 (7.7%)

0.1

Death- 1st year (%)

19 (5.3%)

6 (2.3%)

13 (12.9%)

< 0.001

8 (7.9%)

0 (0%)

8 (22.2%)

< 0.001

11 (4.2%)

6 (3.1%)

5 (7.7%)

0.2

Death- 2nd year (%)

35 (9.7%)

12 (4.6%)

23 (22.8%)

< 0.001

13 (12.9%)

1 (1.5%)

12 (33.3%)

< 0.001

22 (8.4%)

11 (5.6%)

11 (16.9%)

< 0.01

Cardiac death- 1st year (%)

4 (1.1%)

1 (0.4%)

3 (3.0%)

0.1

2 (2.0%)

0 (0%)

2 (5.6%)

0.1

2 (0.8%)

1 (0.5%)

1 (1.5%)

0.4

Cardiac death- 1st + 2nd years (%)

8 (2.2%)

2 (0.8%)

6 (5.9%)

< 0.01

4 (4.0%)

1 (1.5%)

3 (8.3%)

0.1

4 (1.5%)

1 (0.5%)

3 (4.6%)

< 0.05

Hospitalizations- 1st month

0.2 ± 0.6

0.1 ± 0.4

0.3 ± 1.0

< 0.05

0.3 ± 0.9

0.2 ± 0.4

0.4 ± 1.4

0.2

0.2 ± 0.4

0.1 ± 0.3

0.3 ± 0.6

< 0.05

Hospitalizations- 1st year

1.1 ± 2.0

0.8 ± 1.4

1.9 ± 3.0

0.001

1.5 ± 3.1

0.8 ± 1.6

2.8 ± 4.5

< 0.05

1.0 + 1.4

0.9 ± 1.3

1.4 ± 1.7

< 0.05

Hospitalizations- 1st + 2nd year

1.7± 2.7

1.3 ± 1.9

2.8 ± 4.0

< 0.001

2.3 ± 4.0

1.6 ± 2.2

3.9 ± 5.8

< 0.05

1.5 ± 2.0

1.2 ± 1.8

2.3 ± 2.3

< 0.01

Cardiac hospitalizations- 1st year

0.7 ± 1.2

0.5 ± 1.0

1.1 ± 1.7

< 0.005

0.9 + 1.7

0.6 ± 1.3

1.5 ± 2.2

< 0.05

0.6 ± 0.9

0.5 ± 0.8

0.8 ± 1.2

< 0.05

Cardiac hospitalizations- 1st + 2nd years

1.0 ± 1.7

0.8 ± 1.3

1.6 ± 2.3

< 0.001

1.5 + 2.3

1.2 ± 1.8

2.2 ± 2.9

0.1

0.8 ± 1.3

0.7 ± 1.1

1.3 ± 1.7

< 0.01

1st Year catheterization

0.3± 0.6

0.4 ± 0.6

0.3 ± 0.5

0.4

0.3 + 0.6

0.3 ± 0.6

0.3 ± 0.5

1

0.3 ± 0.6

0.4 ± 0.6

0.3 ± 0.5

0.4

TLR (%)

45 (12.4%)

30 (11.5%)

15 (14.9%)

0.4

15 (14.9%)

8 (12.3%)

7 (19.4%)

0.4

30 (11.5%)

22 (11.2%)

8 (12.3%)

0.8

Additional DEB (%)

17 (4.7%)

14 (5.4%)

3 (3.0%)

0.4

6 (5.9%)

4 (6.2%)

2 (5.6%)

1

11 (4.2%)

10 (5.1%)

1 (1.5%)

0.3

Cerebrovascular accident- 1st year (%)

7 (2.0%)

4 (1.5%)

3 (3.0%)

0.4

2 (2.0%)

1 (1.5%)

1 (2.8%)

1

5 (1.9%)

3 (1.5%)

2 (3.1%)

0.6

Hemorrhages- 1st year

0.05 ± 0.3

0.03 ± 0.2

0.08 ± 0.4

0.2

0.05 ± 0.3

0.03 ± 0.2

0.08 ± 0.4

0.4

0.05 ± 0.2

0.04 ± 0.2

0.08 ± 0.3

0.3

  1. DEB Drug eluting balloon, eGFR Estimated glomerular filtration rate, MACE Major adverse cardiac events, MI Myocardial infarction, TLR Target lesion revascularization
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