Table 1 Clinical characteristics and histopathological features of study participants with and without tubular atrophy/interstitial fibrosis (T)
Characteristics | All participants (n = 291) | IgAN without T (n = 174) | IgAN with T (n = 117) | p value |
|---|---|---|---|---|
MAP (mmHg) | 96.30 (12.75) | 94.90 (12.43) | 98.40 (12.97) | 0.023 |
Scr (μmol/L) | 92.73 (47.14) | 77.52 (28.05) | 115.35 (59.31) | < 0.001 |
eGFR (mL/min/1.73m2) | 90.87 (69.14) | 98.11 (29.11) | 80.10 (102.43) | < 0.001 |
Proteinuria (g/24 h) | 1.71 (2.51) | 1.77 (2.71) | 1.62 (2.20) | 0.056 |
Oxford classification | ||||
 M0/M1 (% of M1) | 272/19 (6.53) | 161/13 (7.47) | 111/6 (5.13) | 0.428 |
 E0/E1 (% of E1) | 259/32 (11.00) | 157/17 (9.77) | 102/15 (12.82) | 0.415 |
 S0/S1 (% of S1) | 97/194 (66.67) | 80/94 (54.02) | 17/100 (85.47) | < 0.001 |
T0/T1/T2 (% of [T1 + T2]) | 174/93/24 (40.2) | – | – | – |
C0/C1/C2 (% of [C1 + C2]) | 227/56/8 (21.99) | 140/30/4 (19.54) | 87/26/4 (25.64) | 0.46 |