Table 2 Clinical and histological characteristics influencing the effective proteinuria reduction frequency (a reduction in proteinuria of at least 50%) using univariate and multivariate logistic regression
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
Characteristic | OR | 95%CI | P value | OR | 95%CI | P value |
Age (years) | 1.001 | (0.952,1.053) | 0.961 | 1.028 | (0.947,1.115) | 0.511 |
Sex (male/female) | 2.308 | (0.747,7.128) | 0.146 | 1.475 | (0.272,8.000) | 0.652 |
Proteinuria level before IS therapy (g/d) | 1.024 | (0.813,1.290) | 0.838 | 0.883 | (0.580,1.344) | 0.562 |
Baseline eGFR (ml/min/1.73 m2) | 1.009 | (0.990,1.028) | 0.357 | 0.988 | (0.960,1.017) | 0.415 |
Baseline proteinuria (g/d) | 1.561 | (0.815,2.992) | 0.180 | 2.175 | (0.845,3.597) | 0.107 |
Oxford Classification | ||||||
M 0/1 | 0.514 | (0.129,2.052) | 0.346 | 0.206 | (0.020,2.092) | 0.182 |
E 0/1 | 0.665 | (0.216,2.050) | 0.477 | 0.478 | (0.071,3.207) | 0.394 |
S 0/1 | 0.124 | (0.034,0.452) | 0.232 | 0.049 | (0.007,0.322) | 0.486 |
T 0/1/2 | 0.525 | (0.203,1.359) | 0.184 | 0.680 | (0.104,4.458) | 0.688 |
C 0/1/2 | 0.657 | (0.230,1.876) | 0.433 | 1.039 | (0.209,5.164) | 0.962 |
Optimal RAASi therapy | 0.259 | (0.025,2.675) | 0.259 | 0.255 | (0.020,3.198) | 0.290 |
HCQ therapy | 1.364 | (0.457,4.071) | 0.578 | 0.478 | (0.071,3.207) | 0.447 |
Conventional IS therapy | 0.733 | (0.246,2.189) | 0.578 | 0.795 | (0.252,2.509) | 0.696 |