Skip to main content

Table 2 Clinical and histological characteristics influencing the effective proteinuria reduction frequency (a reduction in proteinuria of at least 50%) using univariate and multivariate logistic regression

From: Effect of hydroxychloroquine in patients with IgA nephropathy with insufficient responses to immunosuppressive therapy: a retrospective case-control study

  Univariate   Multivariate  
Characteristic OR 95%CI P value OR 95%CI P value
Age (years) 1.001 (0.952,1.053) 0.961 1.028 (0.947,1.115) 0.511
Sex (male/female) 2.308 (0.747,7.128) 0.146 1.475 (0.272,8.000) 0.652
Proteinuria level before IS therapy (g/d) 1.024 (0.813,1.290) 0.838 0.883 (0.580,1.344) 0.562
Baseline eGFR (ml/min/1.73 m2) 1.009 (0.990,1.028) 0.357 0.988 (0.960,1.017) 0.415
Baseline proteinuria (g/d) 1.561 (0.815,2.992) 0.180 2.175 (0.845,3.597) 0.107
Oxford Classification
 M 0/1 0.514 (0.129,2.052) 0.346 0.206 (0.020,2.092) 0.182
 E 0/1 0.665 (0.216,2.050) 0.477 0.478 (0.071,3.207) 0.394
 S 0/1 0.124 (0.034,0.452) 0.232 0.049 (0.007,0.322) 0.486
 T 0/1/2 0.525 (0.203,1.359) 0.184 0.680 (0.104,4.458) 0.688
 C 0/1/2 0.657 (0.230,1.876) 0.433 1.039 (0.209,5.164) 0.962
 Optimal RAASi therapy 0.259 (0.025,2.675) 0.259 0.255 (0.020,3.198) 0.290
 HCQ therapy 1.364 (0.457,4.071) 0.578 0.478 (0.071,3.207) 0.447
 Conventional IS therapy 0.733 (0.246,2.189) 0.578 0.795 (0.252,2.509) 0.696
\