Table 1 The basic characteristics of 7 patients affected by Nocardia
From: Nocardiosis in glomerular disease patients with immunosuppressive therapy
Patient | Sex | Age | Smoking history | DM | Renal disease | Renal histology | Baseline eGFR (mL/min/1.73m2) | Baseline hematuria | Baseline albumin | Methylprednisolone | Immunosuppressor | Baseline lymphocytes count (109/L) | Time to remission of kidney disease | Time between kidney disease diagnosis and nocardiosis | Other concomitant disease | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
serum (g/L) | urine | dose (mg qd) | course | category | dose | course | |||||||||||||
1 | Male | 50–60 | 20a,20 years | – | NS | membranous nephropathy | 32.97 | + | 29.6 | 3274.34 mg/d | 16 | 6 months | tacrolimus | 0.5-1 mg qod, 16.10 ng/mL | 6 months | 1.83 | – | 2 years | – |
2 | Male | 20–30 | – | SDM | NS | HBV associated glomerulonephritis (membranous nephropathy) | 155.5 | – | 22.5 | 685.96 mg/d | 16 | 5 months | – | – | – | 1.18 | – | 9 months | Chronic HBV infection |
3 | Female | 60–70 | – | – | Lupus nephritis | – | 29.79 | + | 26.1 | 437.78 mg/d | 16 | 2 months | cytoxan | 0.4 g in total | – | 0.53 | – | 1 year | Hypertension; Cerebral infarction |
4 | Male | 60–70 | – | DM | NS | – | 74.41 | – | 30.6 | – | 32 | 4 months | – | – | – | 0.45 | 4 months | 4 months | – |
5 | Male | 50–60 | 40a, 30 years | – | NS | membranous nephropathy | 115.25 | – | 30.2 | + | 28 | 4 months | – | – | – | 0.87 | 6 months | 6 months | Hypertension Cerebral infarction |
6 | Female | 50–60 | – | SDM | NS | – | 99.35 | + | 28.3 | + | 20 | 6 months | tacrolimus | 1 mg qd, 9.4 ng/mL | 2 months | 0.67 | – | 6 months | – |
7 | Female | 50–60 | – | SDM | IgA nephropathy | IgA nephropathy (FSGS) | 107.26 | +++ | 30.9 | + | 40 | 4 months | – | – | – | 0.62 | – | 6 months | Iatrogenic Cushing’s disease |