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Table 1 Patients characteristics

From: User of angiotensin-converting-enzyme inhibitor and/or angiotensin II receptor blocker might be associated with vascular calcification in predialysis chronic kidney disease patients: a retrospective single-center observational study

A

 

B

 

N

121

N

90

Age, years

71 ± 12

Age, years

72 (63–78)

Men, n (%)

72 (60)

Men, n (%)

54 (60)

Serum phosphate (mg/dL)

3.9 ± 1.1

Serum phosphate (mg/dL)

3.9 ± 1.1

eGFR (mL/min/1.73 m2)eGFR (mL/min/1.73 m2)

20.2 (11.8–40.3)

eGFR (mL/min/1.73 m2)eGFR (mL/min/1.73 m2)

21.3 (12–50.2)

Log [eGFR]

3.1 ± 0.8

Log [eGFR]

3.1 ± 0.8

Calcification Volume (mL)

8.94 (3.26–18.9)

Calcification Volume (mL)

8.0 (3.1–19.3)

Calc/BSA (mL/m2)Calc/BSA (mL/m2)

5.62 (2.01–12.7)

Calc/BSA (mL/m2)Calc/BSA (mL/m2)

5.26 (1.96–13.2)

Log [Calc/BSA]

1.67 ± 1.20

Log [Calc/BSA]

1.66 (0.67–2.58)

Systolic Blood Pressure (mmHg)

134 ± 20

Systolic Blood Pressure (mmHg)

133 ± 20

Hypertension (n(%))

98 (81)

Hypertension (n(%))

69 (77)

Diabetes mellitus (n (%))

54 (45)

Diabetes mellitus (n (%))

38 (42)

Dyslipidemia (n (%))

69 (57)

Dyslipidemia (n (%))

49 (54)

LDL-C (mg/dL)

118 ± 66

LDL-C (mg/dL)

116 ± 65

Malignancy (n (%))

35 (29)

Malignancy (n (%))

30 (33)

Medications

Medications

 Warfarin User (n (%))

14 (12)

 Warfarin User (n (%))

12 (13)

 Vitamin D User (n (%))

12 (10)

 Vitamin D User (n (%))

8 (9)

 Phosphate-Binding Agent User (n (%))

13 (11)

 Phosphate-Binding Agent User (n (%))

8 (9)

 Diuretics user (n (%))

67 (55)

 Diuretics user (n (%))

50 (56)

 ACEI/ARB User (n (%))

48 (40)

ACEI/ARB Duration

  

 None or < 6 months (n (%))

42 (47)

  

 6 months ≤ <  2 years (n (%))

7 (8)

  

 2 years ≤ (n (%))

41 (46)

  1. (A) N = 121, (B) N = 90 where patients whose history of ACEI/ARB use were unknown are excluded. eGFR estimated glomerular filtration rate, Calc calcification volume, BSA body surface area calculated with Fujimoto’s formula, LDL-C low-density lipoprotein cholesterol, ACEI angiotensin-converting-enzyme inhibitor, ARB angiotensin II receptor blocker