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Table 2 Multivariate linear regression analyses for the outcome of log[Calc/BSA]

From: User of angiotensin-converting-enzyme inhibitor and/or angiotensin II receptor blocker might be associated with vascular calcification in predialysis chronic kidney disease patients: a retrospective single-center observational study

 

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

Model 7

Model 8

Model 9

Adjusted R2

0.451

0.531

0.498

0.450

0.554

0.558

0.569

0.576

0.576

Age

0.0587

p < 0.0001

0.0639

p < 0.0001

0.0574

p < 0.0001

0.0577

p < 0.0001

0.0626

p < 0.0001

0.0617

p < 0.0001

0.0576

p < 0.0001

0.0607

p < 0.0001

0.0599

p < 0.0001

Male

0.2741

p = 0.0014

0.2474

p = 0.0025

0.3097

p = 0.0002

0.2695

p = 0.0017

0.2818

p = 0.0005

0.2859

p = 0.0004

0.2427

p = 0.0030

0.2513

p = 0.0020

0.2508

p = 0.0021

Log[eGFR]

−0.2344

p = 0.0214

−0.0603

p = 0.5993

−0.2573

p = 0.0086

−0.2268

p = 0.0264

−0.0872

p = 0.4386

− 0.0796

p = 0.4777

− 0.00033

p = 0.9978

− 0.00135

p = 0.9911

0.0100

p = 0.9338

Phosphate

–

0.2304

p = 0.0085

–

–

0.2161

p = 0.0116

0.2088

p = 0.0143

0.1707

p = 0.055

0.1503

p = 0.0874

0.1597

p = 0.0710

DM

–

0.2883

p = 0.0003

–

–

0.2373

p = 0.0027

0.2248

p = 0.0045

0.1892

p = 0.0174

0.1884

p = 0.0169

0.1819

p = 0.0213

SBP

–

–

–

–

–

0.0055

p = 0.1362

0.00552

p = 0.155

0.0056

p = 0.1497

0.00574

p = 0.1374

warfarin

–

–

–

0.1220

p = 0.3450

–

–

0.1295

p = 0.2664

–

0.1183

p = 0.3068

ACEI/ARB

–

–

0.2781

p = 0.0007

–

0.2028

p = 0.0107

0.1987

p = 0.0119

0.1677

p = 0.0487

0.1671

p = 0.0478

0.1685

p = 0.0461

Hypertension

–

–

–

–

–

–

0.1340

p = 0.2259

0.1130

p = 0.3048

0.1170

p = 0.2884

Dyslipidemia

–

–

–

–

–

–

−0.0808

p = 0.3340

−0.1013

p = 0.2258

− 0.0977

p = 0.2429

LDL-C

–

–

–

–

–

–

−0.00062

p = 0.6221

− 0.00073

p = 0.5620

− 0.00066

p = 0.6001

Diuretics

–

–

–

–

–

–

0.1696

p = 0.0392

0.1809

p = 0.0266

0.1745

p = 0.0327

Malignancy

–

–

–

–

–

–

–

−0.1412

p = 0.0929

− 0.1361

p = 0.1056

  1. β values (upper line) and statistical p values (lower line) are shown in various regression models. The number of patients analyzed here are 121. The effects of age, phosphate, systolic blood pressure (SBP), and low-density lipoprotein cholesterol (LDL-C) are shown as per 1 year, per 1 mg/dL, per 1 mmHg and 1 mg/dL, respectively. Calc, calcification volume, BSA body surface area calculated with Fujimoto’s formula, eGFR estimated glomerular filtration rate, DM diabetes mellitus, SBP systolic blood pressure, LDL-C low-density lipoprotein cholesterol, ACEI angiotensin-converting-enzyme inhibitor, ARB angiotensin II receptor blocker
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BMC Nephrology

ISSN: 1471-2369

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