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Fig. 3 | BMC Nephrology

Fig. 3

From: Immunohistochemical study for the expression of leukocyte adhesion molecules, and FGF23 and ACE2 in P. gingivalis LPS-induced diabetic nephropathy

Fig. 3

Immunostaining of Mac-1 in the diabetic mouse kidney with Pg-LPS-induced nephropathy. Hematoxylin-Eosin staining (HE) (left column), immunostaining for Mac-1 (red) (center column), and merged immunostaining for Mac-1 and podoplanin (green) (right column), with DAPI staining of nuclei (blue). The glomerular epithelial cells are immunostained by anti-podoplanin to be able to discriminate glomeruli (arrows). Mac-1-positive cells (arrowheads) were identified in the whole renal parenchyma (arrowheads) of LPS-ICR (top row) and STZ-ICR (middle row) at a similar level while the number of Mac-1-positive cells increased in LPS-STZ (bottom row). Podoplanin-positive macrophages were also identified in diabetic mouse kidneys (yellow arrows). Bars: 100 μm

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BMC Nephrology

ISSN: 1471-2369

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